4 products were found matching "Cay13612"!
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COVID-19 Research
Nitazoxanide
Item number: Cay13692-10
Nitazoxanide is a prodrug form of the antiparasitic tizoxanide (Cay-13693), an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR). It inhibits growth of the parasite C. parvum in MDBK cells when used at a concentration of 10 µg/ml. It is active against M. tuberculosis and M. bovis (MIC = 16 µg/ml for both) and...
| Keywords: | NSC 697855, NTZ, 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-benzamide |
| Application: | Pyruvate-ferredoxin oxidoreductase inhibitor |
| CAS | 55981-09-4 |
| MW: | 307.3 D |
From 66.00€
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MLN8237
Item number: Cay13602-10
MLN8237 is an inhibitor of Aurora A kinase (IC50 = 1 nM). It is selective for Aurora A over Aurora B kinase (IC50 = 396.5 nM). MLN8237 (50 nM) induces cell cycle arrest at the G2/M phase and chromosomal misalignment in HCT116 colon cancer cells. It inhibits tumor growth in a Calu-6 non-small cell lung cancer (NSCLC)...
| Keywords: | Alisertib, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy benzoic acid |
| Application: | Aurora A kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.9 D |
From 43.00€
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AS-041164
Item number: Cay13622-10
The phosphatidylinositol 3-kinases (PI3Ks) are lipid and protein kinases involved in diverse biological processes, including cell growth, migration, and metabolism. AS-041164 is a potent inhibitor of PI3K with selectivity for the class IB isoform PI3Kgamma (IC50 = 70 nM), compared to PI3Kalpha (IC50 = 240 nM),...
| Keywords: | 5-(1,3-benzodioxol-5-ylmethylene)-2,4-thiazolidinedione |
| Application: | PI3K inhibitor |
| CAS | 6318-41-8 |
| MW: | 249.2 D |
From 97.00€
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ACS 67
Item number: Cay13619-25
Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug for the treatment of glaucoma. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endogenous esterase enzymes. The free acid form is 200 times more potent...
| Keywords: | 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl ester,... |
| Application: | Latanoprost analog |
| CAS | 1088434-86-9 |
| MW: | 598.8 D |
From 105.00€
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