- Search results for Cay13610
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14 products were found matching "Cay13610"!
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Item number: Cay13610-500
13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly...
Keywords: | 13,14-dihydro PGE1, PGE0, 9-oxo-11alpha,15S-dihydroxy-prostan-1-oic acid |
Application: | ADP-induced platelet aggregation inhibitor |
CAS | 19313-28-1 |
MW: | 356.5 D |
From 64.00€
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Item number: Cay13336-10
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and growth related oncogene alpha (Gro-alpha, CXCL1). IL-8 and Gro-alpha are pro-inflammatory CXC chemokines that act as chemoattractants, especially for neutrophils, and promote angiogenesis. SB...
Keywords: | N-(2-bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)-urea |
Application: | CXCR2 antagonist |
CAS | 182498-32-4 |
MW: | 352.1 D |
From 110.00€
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Item number: Cay11136-10
Phencyclidine (PCP), known more commonly as angel dust, is a psychoactive drug that is regulated as a schedule I compound in the United States. 4-methoxy PCP is an analog of PCP which has recently been commercially produced as a designer drug. It preferentially binds the sigma-2 receptor (Ki = 143 nM) and less...
Keywords: | 4-MeO PCP, 4-MeO Phencyclidine, Methoxydine, 1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine, monohydrochloride |
Application: | Analytical reference standard, PCP analog, Designer drug |
CAS | 2185-93-5 |
MW: | 309.9 D |
From 291.00€
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Item number: Cay13636-10
JWH 398 (Cay-13636) is an analytical reference standard categorized as a synthetic cannabinoid. JWH 398 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.Formal Name: (4-chloro-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone. CAS Number:...
Keywords: | (4-chloro-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone |
Application: | Analytical reference standard, synthetic cannabinoid |
CAS | 1292765-18-4 |
MW: | 375.9 D |
From 241.00€
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Item number: Cay13667-10
The amino acid gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that acts through two families of heteromeric ligand-gated ion channels, GABAA and GABAC and a G protein-coupled receptor, GABAB. Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity...
Keywords: | Agarin, Pantherine, 5-(aminomethyl)-3(2H)-isoxazolone |
Application: | GABAA agonist |
CAS | 2763-96-4 |
MW: | 114.1 D |
From 98.00€
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Item number: Cay13668-10
Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mediate the hydrolysis of the endocannabinoids arachidonoyl ethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL 195 is a potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively). It poorly inhibits neuropathy...
Keywords: | 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate |
Application: | FAAH / MAGL inhibitor |
CAS | 1210004-12-8 |
MW: | 433.5 D |
From 82.00€
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Item number: Cay13619-10
Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug for the treatment of glaucoma. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endogenous esterase enzymes. The free acid form is 200 times more potent...
Keywords: | 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl ester,... |
Application: | Latanoprots analog |
CAS | 1088434-86-9 |
MW: | 598.8 D |
From 105.00€
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Item number: Cay13602-10
MLN8237 is an inhibitor of Aurora A kinase (IC50 = 1 nM). It is selective for Aurora A over Aurora B kinase (IC50 = 396.5 nM). MLN8237 (50 nM) induces cell cycle arrest at the G2/M phase and chromosomal misalignment in HCT116 colon cancer cells. It inhibits tumor growth in a Calu-6 non-small cell lung cancer (NSCLC)...
Keywords: | Alisertib, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy benzoic acid |
Application: | Aurora A kinase inhibitor |
CAS | 1028486-01-2 |
MW: | 518.9 D |
From 43.00€
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Item number: Cay13653-10
ABT-869 is a dual VEGFR and PDGFR family kinase inhibitor (IC50s = 0.003, 0.004, 0.004, 0.19, 0.066, 0.003, and 0.014 µM for VEGFR1, VEGFR2, FLT3, VEGFR3, PDGFRbeta, CSF-1R, and KIT, respectively). It is selective for these kinases over other tyrosine kinases, including RET, FGFR, Src, EGFR, and c-Met (IC50s = 1.9,...
Keywords: | Linifanib, N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)-urea |
Application: | RTK inhibitor |
CAS | 796967-16-3 |
MW: | 375.4 D |
From 54.00€
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Item number: Cay13630-10
13,14-dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)-PGE1) is an analog of 13,14-dihydro-PGE1 (Cay-13610), which has the hydroxyl group at C-15 in the unnatural R configuration.Formal Name: 11alpha,15R-dihydroxy-9-oxo-prostan-1-oic acid. CAS Number: 201848-10-4. Synonyms: 13,14-dihydro-15(R)-PGE1. Molecular...
Keywords: | 13,14-dihydro-15(R)-PGE1, 9-oxo-11alpha,15R-dihydroxy-prostan-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 201848-10-4 |
MW: | 356.5 D |
From 86.00€
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Item number: Cay13622-10
The phosphatidylinositol 3-kinases (PI3Ks) are lipid and protein kinases involved in diverse biological processes, including cell growth, migration, and metabolism. AS-041164 is a potent inhibitor of PI3K with selectivity for the class IB isoform PI3Kgamma (IC50 = 70 nM), compared to PI3Kalpha (IC50 = 240 nM),...
Keywords: | 5-(1,3-benzodioxol-5-ylmethylene)-2,4-thiazolidinedione |
Application: | PI3K inhibitor |
CAS | 6318-41-8 |
MW: | 249.2 D |
From 97.00€
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Item number: Cay13639-10
The CXC chemokine receptor-4 (CXCR4) is a G protein-coupled receptor that is specific for stromal cell-derived factor-1 (SDF-1/ CXCL12). Activation of CXCR4 promotes homing of hematopoietic stem cells, chemotaxis and quiescence of lymphocytes, and growth and metastasis of certain cancer cell types. Moreover, CXCR4...
Keywords: | N1,N4-di-2-pyridinyl-1,4-benzenedimethanamine |
Application: | CXCR4 antagonist |
CAS | 55778-02-4 |
MW: | 290.4 D |
From 26.00€
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