- Search results for Cay13571
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8 products were found matching "Cay13571"!
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Item number: Cay13557-1
The poly(ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as methylation of N3-adenine, which activates the base excision repair process. PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA...
Keywords: | Anti-ADPRT, Anti-PARP1, Anti-PARP-1, EC=2.4.2.30, Anti-ADPRT 1, Anti-Poly[ADP-ribose] synthase 1, Anti-Poly [ADP-ribose]... |
Application: | WB, FC (intracellular) |
Host: | Mouse |
Species reactivity: | human |
481.00€
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Item number: Cay13576-1
PIKfyve is a phosphoinositide kinase (PIK) that contains a FYVE-type zinc finger domain, which binds phosphatidylinositol 3-phosphate (PI3P). PIKfyve phosphorylates PI3P to produce PI-(3,5)-P2, which is involved in cellular processes including membrane trafficking and cytoskeletal reorganization. YM-201636 is a...
Keywords: | 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide |
Application: | PIKfyve inhibitor |
CAS | 371942-69-7 |
MW: | 467.5 D |
From 68.00€
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Item number: Cay13574-1
The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20alpha-HSD and the other three being 3alpha-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin,...
Keywords: | NSC 109116, 5-bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid |
Application: | AKR1C1 inhibitor |
CAS | 4906-68-7 |
MW: | 293.1 D |
From 86.00€
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Item number: Cay13575-1
PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV, Ki = 4.3 µM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 µM, respectively). PSI-6130 also inhibits replication of HCV...
Keywords: | (2'R)-2'-deoxy-2'-fluoro-2'-methyl-cytidine |
Application: | HCV NS5B polymerase inhibitor |
CAS | 817204-33-4 |
MW: | 259.2 D |
From 125.00€
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Item number: Cay13578-1
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor I is a potent, cell-permeable inhibitor of mouse VEGFR2...
Keywords: | SU 5408, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, ethyl ester |
Application: | Mouse VEGFR2 inhibitor |
CAS | 15966-93-5 |
MW: | 310.4 D |
From 92.00€
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Item number: Cay13757-1
NF-kappaB p65 is a ubiquitously expressed transcription factor that is a subunit of the NF-kappaB complex and is encoded by the RELA gene in humans. It is composed of an N-terminal Rel homology domain, which contains the nuclear localization signal (NLS), and mediates dimerization, nuclear localization, and DNA and...
Keywords: | Nuclear Factor NF-kappaB (p65) subunit, Transcription Factor p65 |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
395.00€
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Item number: Cay13057-1
3-methyl Benzamideoxime is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: N-hydroxy-3-methyl-benzenecarboximidamide. CAS Number: 40067-82-1. Synonyms: m-Tolylamideoxime. Molecular Formula: C8H10N2O. Formula Weight: 150.2. Purity: >98%. Formulation: (Request formulation change), A...
Keywords: | m-Tolylamideoxime, N-hydroxy-3-methyl-benzenecarboximidamide |
Application: | Synthetic intermediate, Pharmaceutical synthesis |
CAS | 40067-82-1 |
MW: | 150.2 D |
From 50.00€
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Item number: Cay13527-1
Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer...
Keywords: | NSC 615488, PAB,... |
Application: | Fungicide |
CAS | 82508-31-4 |
MW: | 432.5 D |
From 60.00€
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