- Search results for Cay13551
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13 products were found matching "Cay13551"!
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Item number: Cay13355-1
Geldanamycin is a benzoquinone ansamycin antibiotic which binds heat shock protein 90 (Hsp90) and its paralog GRP94, altering their actions. Through its interaction with these chaperones, geldanamycin indirectly affects numerous client proteins with roles in diverse cellular processes, including gene expression,...
Keywords: | NSC 122750,... |
Application: | Antibiotic |
CAS | 30562-34-6 |
MW: | 560.6 D |
From 77.00€
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Item number: Cay13335-1
SB 218078 is an inhibitor of checkpoint kinase 1 (Chk1) that blocks phosphorylation of cdc25 with an IC50 value of 15 nM. It less potently inhibits cdc2 and PKC (IC50s = 250 and 1,000 nM, respectively) and causes 85% inhibition of PKD1 at 1 µM. SB 218078 releases G2 cell cycle arrest induced by gamma-irradiation or...
Keywords: | 9,10,11,12-tetrahydro-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione |
Application: | Chk1 inhibitor |
CAS | 135897-06-2 |
MW: | 393.4 D |
189.00€
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Item number: Cay13351-1
Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.Formal Name:...
Keywords: | C14:0, NSC 5028, tetradecanoic acid |
Application: | N-myristoylation |
CAS | 544-63-8 |
MW: | 228.4 D |
From 20.00€
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Item number: Cay11351-5
Verruculogen is a tremorgenic mycotoxin isolated from species of Penicillium, Aspergillus, and other fungi. It selectively inhibits the activation of large-conductance calcium-activated potassium channels (KCa1.1/BK) potassium channels by charybdotoxin with a K1/2 value of 170 nM. Verruculogen also promotes the...
Keywords: | NA 209A, TR 1,... |
Application: | Inhibitor of BK channel activation by charybdotoxin |
CAS | 12771-72-1 |
MW: | 511.6 D |
From 134.00€
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Item number: Cay13511-1
1-Deoxysphinganine is an atypical sphingolipid that lacks the C1-hydroxyl group of canonical sphinganine and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis. Plasma levels of 1-deoxysphinganine are increased in patients with hereditary...
Keywords: | 1-deoxySA, ES-285, Spisulosine, 2S-amino-3R-octadecanol |
Application: | Atypical sphingolipid |
CAS | 196497-48-0 |
MW: | 285.5 D |
From 158.00€
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Item number: Cay13554-1
LSD1 is a flavin-containing nuclear protein having a N-terminal SWIRM domain, a C-terminal FAD-binding motif, and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release...
Keywords: | Amine Oxidase (flavin containing) Domain 2 |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
432.00€
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Item number: Cay13557-1
The poly(ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as methylation of N3-adenine, which activates the base excision repair process. PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA...
Keywords: | Anti-ADPRT, Anti-PARP1, Anti-PARP-1, EC=2.4.2.30, Anti-ADPRT 1, Anti-Poly[ADP-ribose] synthase 1, Anti-Poly [ADP-ribose]... |
Application: | WB, FC (intracellular) |
Host: | Mouse |
Species reactivity: | human |
481.00€
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Item number: Cay13255-1
U-69593 (Cay-13255) is an analytical reference standard categorized as an opioid. This product is intended for research and forensic applications.Formal Name: N-methyl-2-phenyl-N-(7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl)acetamide. Molecular Formula: C22H32N2O2. Formula Weight: 356.5. Purity: >95%. Formulation:...
Keywords: | N-methyl-2-phenyl-N-(7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl)acetamide |
Application: | Analytical reference standard, Opioid, Kappa1-opioid receptor agonist |
MW: | 356.5 D |
From 92.00€
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Item number: Cay13855-1
NFAT inhibitor is a peptide inhibitor of the transcription factor nuclear factor of activated T cells (NFAT). It binds to the NFAT recognition site on the protein phosphatase calcineurin (IC50 = 25 pM) but does not inhibit calcineurin phosphatase activity when used at a concentration of 100 µM. NFAT inhibitor...
Keywords: | L-methionyl-L-alanylglycyl-L-prolyl-L-histidyl-L-prolyl-L-valyl-L-isoleucyl-L-valyl-L-isoleucyl-L-threonylglycyl-L-prolyl-... |
Application: | NFAT Inhibitor |
CAS | 249537-73-3 |
MW: | 1683.9 D |
From 110.00€
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Item number: Cay13755-1
NF-kappaB is a transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis, and inflammation....
Application: | IHC, WB |
Host: | Mouse |
Species reactivity: | human |
472.00€
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Item number: Cay13535-1
Histone H2A is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei. It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to a variety of...
Application: | WB, ELISA |
Host: | Rabbit |
Species reactivity: | human |
409.00€
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Item number: Cay13575-1
PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV, Ki = 4.3 µM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 µM, respectively). PSI-6130 also inhibits replication of HCV...
Keywords: | (2'R)-2'-deoxy-2'-fluoro-2'-methyl-cytidine |
Application: | HCV NS5B polymerase inhibitor |
CAS | 817204-33-4 |
MW: | 259.2 D |
From 125.00€
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