- Search results for Cay13543-%25
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8 products were found matching "Cay13543-%25"!
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Item number: Cay13345-25
Hydrogen sulfide (H2S) is a gaseous mediator which, like nitric oxide (NO), has numerous profound actions in mammalian physiology. GYY 4137 is a water-soluble, slow-releasing hydrogen sulfide (H2S) donor. When given intravenously, it demonstrates vasodilator and anti-hypertensive activity in rats, in either the...
Keywords: | (p-methoxyphenyl)morpholino-phosphinodithioic acid |
Application: | Hydrogen sulfide donor |
CAS | 106740-09-4 |
MW: | 377.5 D |
From 82.00€
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Item number: Cay13523-25
The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids (apelin-36, apelin-17, and apelin-13, respectively). Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM (the...
Keywords: | L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenyl... |
Application: | APJ receptor ligand |
MW: | 1550.8 D |
From 77.00€
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COVID-19 Research
Item number: Cay13533-25
E-64d is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases and has diverse biological activities. It is a synthetic analog of E-64 (Cay-10007963) and prodrug form of E-64c (Cay-10007964) that inhibits calpain and the cysteine proteases cathepsins F, -K, -B, -H, and...
Keywords: | Aloxistatin, E-64c ethyl ester, EP 453, EST, Loxistatin, NSC 694281,... |
Application: | Protease inhibitor |
CAS | 88321-09-9 |
MW: | 342.4 D |
From 66.00€
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Item number: Cay13243-25
Soluble adenylyl cyclase mediates bicarbonate-stimulated production of the ubiquitous second messenger adenosine 3',5'-cyclic mononucleotide (cAMP). It is abundantly expressed in sperm, in fluid transporting tissues such as kidney cortex and medulla, and in other bicarbonate-responsive tissues and cells. KH7 is a...
Keywords: | 2-(1H-benzimidazol-2-ylthio)-2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide, propanoic acid |
Application: | Soluble adenylate cyclase inhibitor |
CAS | 330676-02-3 |
MW: | 419.3 D |
From 109.00€
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Item number: Cay13643-25
The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. PP242 is an inhibitor of the active site of mTOR kinase in...
Keywords: | 2-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol |
Application: | mTOR kinase inhibitor |
CAS | 1092351-67-1 |
MW: | 308.3 D |
From 43.00€
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Item number: Cay13143-25
CAY10587 is a selective FFAR1 (GPR40) agonist (EC50 = 32 nM) that does not exhibit activity on the related FFARs: FFAR2 (GPR43) or FFAR3 (GPR41). At 100 nM, CAY10587 increases glucose-stimulated insulin secretion in the rat insulin-secreting cell line INS-1E.Formal Name:...
Keywords: | 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoic acid |
Application: | FFAR1 agonist, GPR40 agonist |
CAS | 1082058-99-8 |
MW: | 264.3 D |
From 44.00€
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Item number: Cay13043-25
2-Pyridylthioamide is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 2-pyridinecarbothioamide. CAS Number: 5346-38-3. Synonyms: NSC 1606, Picolinic Acid Thioamide. Molecular Formula: C6H6N2S. Formula Weight: 138.2. Purity: >98%. Formulation: (Request formulation change), A crystalline...
Keywords: | NSC 1606, Picolinic Acid Thioamide, 2-pyridinecarbothioamide |
Application: | Synthetic intermediate, Pharmaceutical synthesis |
CAS | 5346-38-3 |
MW: | 138.2 D |
From 15.00€
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Item number: Cay13943-25
FKGK 18 is an inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2). It inhibits GVIA iPLA2 by 99.9% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows 80.8 and 36.8% inhibition, respectively. FKGK 18 inhibits...
Keywords: | 1,1,1-trifluoro-6-(2-naphthalenyl)-2-hexanone |
Application: | iPLA2 inhibitor |
CAS | 1071001-09-6 |
MW: | 280.3 D |
From 163.00€
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