5 products were found matching "Cay13538-%25"!
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(-)-Warfarin
Item number: Cay13531-25
(-)-Warfarin is a component of (±)-warfarin (Cay-13566). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (-)-warfarin slows formation of the...
| Keywords: | (S)-Warfarin, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one |
| Application: | Anti-coagulant |
| CAS | 5543-57-7 |
| MW: | 308.3 D |
From 94.00€
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Resolvin D4
Item number: Cay13835-25
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Cay-90310). It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines. RvD4, at 10 ng/mouse, reduces neutrophil...
| Keywords: | RvD4, (4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxy-6,8,10,13,15,19-docosahexaenoic acid |
| CAS | 1025684-60-9 |
| MW: | 376.5 D |
From 205.00€
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JIB-04
Item number: Cay15338-25
JIB-04 is a pyridine hydrazone that broadly inhibits Jumonji histone demethylases (IC50s values = 230, 340, 435, 445, 855 and 1,100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3, and JMJD2C, respectively). It does not inhibit histone deacetylases and has minimal effect on the iron-containing enzymes methylcytosine...
| Keywords: | JHDM Inhibitor VII, NSC 693627, phenyl-2-pyridinyl-methanone, (E,E)-2-(5-chloro-2-pyridinyl)hydrazone |
| Application: | Jumonji histone demethylase inhibitor |
| CAS | 199596-05-9 |
| MW: | 308.8 D |
From 109.00€
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CAY10626
Item number: Cay13838-25
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3, important second messengers that modulate the activity of downstream targets Akt and mTOR. Aberrant PI3K/Akt is associated with many human cancers. CAY10626 is a...
| Keywords: | N-[2-(dimethylamino)ethyl]-N-methyl-4-[[[[4-[4-(4-morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]ph... |
| Application: | PI3K inhibitor |
| CAS | 1202884-94-3 |
| MW: | 624.7 D |
From 141.00€
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SU6656
Item number: Cay13338-25
The Src family of proto-oncogenic kinases include nine mammalian non-receptor tyrosine kinases that are involved in intracellular signaling and are often relevant to carcinogenesis. SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). It weakly...
| Keywords: | 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
| Application: | Src kinase inhibitor |
| CAS | 330161-87-0 |
| MW: | 371.5 D |
From 32.00€
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