- Search results for Cay13510
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11 products were found matching "Cay13510"!
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Item number: Cay13510-500
11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1. Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2. However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat...
Keywords: | 11-deoxy PGE1, 9-oxo-15S-hydroxy-prost-13E-en-1-oic acid |
Application: | EP2 receptor agonist |
CAS | 37786-00-8 |
MW: | 338.5 D |
From 44.00€
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Item number: Cay13355-10
Geldanamycin is a benzoquinone ansamycin antibiotic which binds heat shock protein 90 (Hsp90) and its paralog GRP94, altering their actions. Through its interaction with these chaperones, geldanamycin indirectly affects numerous client proteins with roles in diverse cellular processes, including gene expression,...
Keywords: | NSC 122750,... |
Application: | Antibiotic |
CAS | 30562-34-6 |
MW: | 560.6 D |
From 77.00€
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Item number: Cay13579-10
Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within...
Keywords: | alpha-ethyl-6-[5-[2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[... |
Application: | Tumor growth inhibitor, Antiprotozoal, Coccidiostat |
CAS | 53003-10-4 |
MW: | 751 D |
From 34.00€
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Item number: Cay13521-10
A Aconitase catalyzes the stereospecific isomerization of citrate to isocitrate in the first step of the citric acid cycle. It acts as an iron regulatory protein (IRP), controlling the translation of proteins involved in iron metabolism when iron is scarce and resumes aconitase activity when iron is abundant....
Keywords: | 3-carboxy-3-deoxy-2-pentulosaric acid, trisodium salt |
Application: | Metabolic studies |
CAS | 89304-26-7 |
MW: | 275 D |
From 43.00€
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COVID-19 Research
Item number: Cay13533-10
E-64d is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases and has diverse biological activities. It is a synthetic analog of E-64 (Cay-10007963) and prodrug form of E-64c (Cay-10007964) that inhibits calpain and the cysteine proteases cathepsins F, -K, -B, -H, and...
Keywords: | Aloxistatin, E-64c ethyl ester, EP 453, EST, Loxistatin, NSC 694281,... |
Application: | Protease inhibitor |
CAS | 88321-09-9 |
MW: | 342.4 D |
From 66.00€
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Item number: Cay13576-10
PIKfyve is a phosphoinositide kinase (PIK) that contains a FYVE-type zinc finger domain, which binds phosphatidylinositol 3-phosphate (PI3P). PIKfyve phosphorylates PI3P to produce PI-(3,5)-P2, which is involved in cellular processes including membrane trafficking and cytoskeletal reorganization. YM-201636 is a...
Keywords: | 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide |
Application: | PIKfyve inhibitor |
CAS | 371942-69-7 |
MW: | 467.5 D |
From 68.00€
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Item number: Cay13562-10
Sterol regulatory element binding proteins (SREBPs) are transcription factors that have pivotal roles in lipogenesis and fat metabolism. The activation of SREBPs requires escort to the Golgi by SREBP cleavage-activating protein (SCAP) followed by proteolytic release of SREBP from the Golgi. Fatostatin is an...
Keywords: | 125B11, 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propyl-pyridine, hydrobromide |
Application: | SREBP activation inhibitor |
CAS | 298197-04-3 |
MW: | 375.3 D |
From 92.00€
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Item number: Cay13527-10
Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer...
Keywords: | NSC 615488, PAB,... |
Application: | Fungicide |
CAS | 82508-31-4 |
MW: | 432.5 D |
From 60.00€
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Item number: Cay13580-10
HDMAPP is a metabolite of the microbial dioxyxylulose-phosphate pathway, which is analogous to the isopentenyl pyrophosphate pathway in mammals. It is a protease-resistant and phosphatase-sensitive pyrophosphate produced by bacteria and plants. HDMAPP is a non-peptide ligand, also called a phosphoantigen, that binds...
Keywords: | HMBPP, mono[(2E)-hydroxy-3-methyl-2-butenyl] ester diphosphoric acid, triammonium salt |
Application: | Microbial deoxyxylulose-phosphate pathway metabolite, TCR ligand |
CAS | 443892-56-6 |
MW: | 313.2 D |
From 102.00€
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Item number: Cay13526-10
(+)-Warfarin is a component of (±)-warfarin (Cay-13566). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (+)-warfarin slows formation of the...
Keywords: | (R)-Warfarin, 4-hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one |
Application: | Anti-coagulant |
CAS | 5543-58-8 |
MW: | 308.3 D |
From 104.00€
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Item number: Cay13597-10
The mammalian target of rapamycin (mTOR) is a serine-threonine kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. Ku-0063794 is a cell-permeable, selective dual inhibitor of mTORC1 and...
Keywords: | rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-benzenemethanol |
Application: | TORC1/2 inhibitor |
CAS | 938440-64-3 |
MW: | 465.5 D |
From 98.00€
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