11 products were found matching "Cay13510"!

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11-deoxy Prostaglandin E1
11-deoxy Prostaglandin E1

Item number: Cay13510-500

11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1. Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2. However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat...
Keywords: 11-deoxy PGE1, 9-oxo-15S-hydroxy-prost-13E-en-1-oic acid
Application: EP2 receptor agonist
CAS 37786-00-8
MW: 338.5 D
From 44.00€ *
Review
Geldanamycin
Geldanamycin

Item number: Cay13355-10

Geldanamycin is a benzoquinone ansamycin antibiotic which binds heat shock protein 90 (Hsp90) and its paralog GRP94, altering their actions. Through its interaction with these chaperones, geldanamycin indirectly affects numerous client proteins with roles in diverse cellular processes, including gene expression,...
Keywords: NSC 122750,...
Application: Antibiotic
CAS 30562-34-6
MW: 560.6 D
From 77.00€ *
Review
Salinomycin
Salinomycin

Item number: Cay13579-10

Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within...
Keywords: alpha-ethyl-6-[5-[2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[...
Application: Tumor growth inhibitor, Antiprotozoal, Coccidiostat
CAS 53003-10-4
MW: 751 D
From 34.00€ *
Review
Oxalomalic Acid (sodium salt)
Oxalomalic Acid (sodium salt)

Item number: Cay13521-10

A Aconitase catalyzes the stereospecific isomerization of citrate to isocitrate in the first step of the citric acid cycle. It acts as an iron regulatory protein (IRP), controlling the translation of proteins involved in iron metabolism when iron is scarce and resumes aconitase activity when iron is abundant....
Keywords: 3-carboxy-3-deoxy-2-pentulosaric acid, trisodium salt
Application: Metabolic studies
CAS 89304-26-7
MW: 275 D
From 43.00€ *
Review
COVID-19 Research
E-64d
E-64d

Item number: Cay13533-10

E-64d is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases and has diverse biological activities. It is a synthetic analog of E-64 (Cay-10007963) and prodrug form of E-64c (Cay-10007964) that inhibits calpain and the cysteine proteases cathepsins F, -K, -B, -H, and...
Keywords: Aloxistatin, E-64c ethyl ester, EP 453, EST, Loxistatin, NSC 694281,...
Application: Protease inhibitor
CAS 88321-09-9
MW: 342.4 D
From 66.00€ *
Review
YM-201636
YM-201636

Item number: Cay13576-10

PIKfyve is a phosphoinositide kinase (PIK) that contains a FYVE-type zinc finger domain, which binds phosphatidylinositol 3-phosphate (PI3P). PIKfyve phosphorylates PI3P to produce PI-(3,5)-P2, which is involved in cellular processes including membrane trafficking and cytoskeletal reorganization. YM-201636 is a...
Keywords: 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide
Application: PIKfyve inhibitor
CAS 371942-69-7
MW: 467.5 D
From 68.00€ *
Review
Fatostatin (hydrobromide)
Fatostatin (hydrobromide)

Item number: Cay13562-10

Sterol regulatory element binding proteins (SREBPs) are transcription factors that have pivotal roles in lipogenesis and fat metabolism. The activation of SREBPs requires escort to the Golgi by SREBP cleavage-activating protein (SCAP) followed by proteolytic release of SREBP from the Golgi. Fatostatin is an...
Keywords: 125B11, 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propyl-pyridine, hydrobromide
Application: SREBP activation inhibitor
CAS 298197-04-3
MW: 375.3 D
From 92.00€ *
Review
Pseudolaric Acid B
Pseudolaric Acid B

Item number: Cay13527-10

Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer...
Keywords: NSC 615488, PAB,...
Application: Fungicide
CAS 82508-31-4
MW: 432.5 D
From 60.00€ *
Review
HDMAPP (ammonium salt)
HDMAPP (ammonium salt)

Item number: Cay13580-10

HDMAPP is a metabolite of the microbial dioxyxylulose-phosphate pathway, which is analogous to the isopentenyl pyrophosphate pathway in mammals. It is a protease-resistant and phosphatase-sensitive pyrophosphate produced by bacteria and plants. HDMAPP is a non-peptide ligand, also called a phosphoantigen, that binds...
Keywords: HMBPP, mono[(2E)-hydroxy-3-methyl-2-butenyl] ester diphosphoric acid, triammonium salt
Application: Microbial deoxyxylulose-phosphate pathway metabolite, TCR ligand
CAS 443892-56-6
MW: 313.2 D
From 102.00€ *
Review
(+)-Warfarin
(+)-Warfarin

Item number: Cay13526-10

(+)-Warfarin is a component of (±)-warfarin (Cay-13566). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (+)-warfarin slows formation of the...
Keywords: (R)-Warfarin, 4-hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one
Application: Anti-coagulant
CAS 5543-58-8
MW: 308.3 D
From 104.00€ *
Review
Ku-0063794
Ku-0063794

Item number: Cay13597-10

The mammalian target of rapamycin (mTOR) is a serine-threonine kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. Ku-0063794 is a cell-permeable, selective dual inhibitor of mTORC1 and...
Keywords: rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-benzenemethanol
Application: TORC1/2 inhibitor
CAS 938440-64-3
MW: 465.5 D
From 98.00€ *
Review