2 products were found matching "Cay13503-%25"!
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NSC 663284
Item number: Cay13303-25
Three genes encode dual specificity phosphatases that are Cdc25 homologs. The phosphatases, Cdc25A through C, are proto-oncogenes and are often over-expressed in cancers. NSC 663284 is a potent, cell-permeable, and irreversible inhibitor of all Cdc25 isoforms, with preference for Cdc25A (IC50 = 29, 95, and 89 nM for...
| Keywords: | Cdc25 Phosphatase Inhibitor II, DA-3003-1, SPS8I1, 6-chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione |
| Application: | Cdc25 inhibitor |
| CAS | 383907-43-5 |
| MW: | 321.8 D |
From 32.00€
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SBC-110736
Item number: Cay23103-25
SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9). It increases LDL receptor (LDLR) levels in HepG2 cells expressing PCSK9 when used at a concentration of 400 nM. SBC-110736 (8 mg/kg per day) reduces plasma total cholesterol levels by a mean of 38% in mice fed a high-fat diet. It...
| Keywords: | N-[4-[[4-(4-methylphenyl)-2-phenyl-1-piperazinyl]carbonyl]phenyl]-acetamide |
| Application: | PCSK9 inhibitor |
| CAS | 1629166-02-4 |
| MW: | 413.5 D |
From 50.00€
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