- Search results for Cay13499-%25
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7 products were found matching "Cay13499-%25"!
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Item number: Cay14399-5
Activation of the p38/mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2 or MK2) pathway has been implicated in promoting pro-inflammatory cytokine production and related inflammatory diseases. MK2 inhibitor IV is a highly selective, non-ATP competitive MK2 inhibitor with an IC50 value of 0.11 µM....
Keywords: | MK 25, 5-(4-chlorophenyl)-N-[4-(1-piperazinyl)phenyl]-N-(2-pyridinylmethyl)-2-furancarboxamide, monohydrochloride |
Application: | MK2 inhibitor |
CAS | 1314118-94-9 |
MW: | 509.4 D |
From 109.00€
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Item number: Cay14993-25
Suc-AAPF-pNA is a chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM), subtilisins, chymotrypsin (Km = 60 µM), chymase (Km = 4 mM), and cyclophilin, but not neutrophil elastase. Release of p-nitroanilide is monitored at 405-410 nm. This substrate can be used for inhibitor screening and kinetic...
Keywords: | Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide,... |
Application: | Chromogenic substrate, Inhibitor screening, Kinetic analyses |
CAS | 70967-97-4 |
MW: | 624.7 D |
From 61.00€
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Item number: Cay14939-25
Rabeprazole is a proton pump inhibitor that selectively and irreversibly inhibits the gastric H+/K+ ATPase (IC50 = 72 nM). It can be activated more rapidly and over a greater pH range than other proton pump inhibitors such as omeprazole (Cay-14880), lansoprazole (Cay-13627), and pantoprazole (Cay-21345). Rabeprazole...
Keywords: | E 3810, LY307640, 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, monosodium salt |
Application: | Proton pump inhibitor |
CAS | 117976-90-6 |
MW: | 381.4 D |
From 43.00€
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Item number: Cay31499-25
Xanthine is a purine base and intermediate in the biosynthesis of uric acid (Cay-16219). It is formed during mammalian purine catabolism in the liver via oxidation of hypoxanthine (Cay-22254) by xanthine oxidase (XO), which also oxidizes xanthine to produce uric acid. Xanthine is also formed from guanine,...
Keywords: | 2,6-Dihydroxypurine, NSC 14664, 3,9-dihydro-1H-purine-2,6-dione |
Application: | Purine base, Uric acid biosynthesis intermediate |
CAS | 69-89-6 |
MW: | 152.1 D |
From 44.00€
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Item number: Cay23499-25
NSC 668036 is an inhibitor of the Dishevelled (Dvl) protein PDZ domain (Kd = 240 µM for mouse Dvl1 PDZ domain). NSC 668036 interacts with Dvl PDZ at the same binding site as Dapper and Frizzled, native binding partners in the Wnt signaling pathway. NSC 668036 (180 ng) reduces expression of the Wnt target gene,...
Keywords: | N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine, (1S)-1-carboxy-2-methylpropyl ester |
Application: | Dishevelled PDZ domain inhibitor |
CAS | 144678-63-7 |
MW: | 460.5 D |
From 50.00€
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Item number: Cay13299-25
Bisindolylmaleimide IV (BIM IV) is a cell permeable inhibitor of protein kinase C (PKC) with IC50 values reported to range from 0.10 to 0.55 µM. BIM IV was designed to be more discriminative than its parent compound, the non-selective PKC inhibitor, staurosporine (Cay-81590). However, BIM IV also inhibits protein...
Keywords: | Arcyriarubin A, BIM IV, 3,4-di-1H-indol-3-yl-1H-pyrrole-2,5-dione |
Application: | PKC inhibitor |
CAS | 119139-23-0 |
MW: | 327.3 D |
From 72.00€
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Item number: Cay10007875-25
CAY10499 is a non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). It also inhibits ATGL, DAGLa, ABHD6, and CES1 by 95, 60, 90, and 95%, respectively, when used at a concentration of 5 mM. CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and...
Keywords: | [4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]-carbamic acid, phenylmethyl ester |
Application: | HSL inhibitor |
CAS | 359714-55-9 |
MW: | 355.3 D |
From 22.00€
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