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Tafamidis
Tafamidis

Item number: Cay13694-25

Tafamidis is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1 = 3 nM, Kd2 = 278 nM) to stabilize the TTR dimer-dimer interface and inhibit tetrameric dissociation. Tafamidis stabilizes wild-type and clinically...
Keywords: PF-06291826, 2-(3,5-dichlorophenyl)-6-benzoxazolecarboxylic acid
Application: TTR kinetic stabilizer, Amyloidogenesis suppressant
CAS 594839-88-0
MW: 308.1 D
From 90.00€ *
Review
N-pentadecanoyl-L-Homoserine lactone
N-pentadecanoyl-L-Homoserine lactone

Item number: Cay13094-25

N-pentadecanoyl-L-Homoserine lactone is an N-acyl homoserine lactone produced by Y. pseudotuberculosis and a bacterial quorum-sensing signaling molecule. It activates the LasR quorum sensing receptor of bacteria in a reporter assay. N-pentadecanoyl-L-Homoserine lactone induces GFP production in a P. putida F117...
Keywords: C15-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-pentadecanamide
Application: Antibiotic
CAS 182359-66-6
MW: 325.5 D
From 60.00€ *
Review