3 products were found matching "Cay13489-%25"!
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Cyclophosphamide (hydrate)
Item number: Cay13849-25
Cyclophosphamide is a nitrogen mustard alkylating agent. It acts as a prodrug and is converted to the active metabolite phosphoramide mustard (Cay-34078) via 4-hydroxycyclophosphamide and aldophosphamide intermediates by cytochrome P450s (CYP450s) in the liver. Cyclophosphamide (50 mg/kg) induces the formation of...
| Keywords: | Endoxan, N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine, monohydrate |
| Application: | Alkylating agent |
| CAS | 6055-19-2 |
| MW: | 279.1 D |
From 43.00€
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Sertraline (hydrochloride)
Item number: Cay14839-25
Sertraline is a selective serotonin reuptake inhibitor (SSRI). It inhibits monoamine uptake by the serotonin transporter (SERT) with an IC50 value of 70 nM. It is selective for SERT over the norepinephrine and dopamine transporters (IC50s = 520 and 720 nM, respectively). Sertraline (3.2-56 mg/kg, s.c.) reduces...
| Keywords: | CP 51,974-1, Lustral, Seserine, Zoloft(TM), (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine,... |
| Application: | Serotonin reuptake / transporter inhibitor |
| CAS | 79559-97-0 |
| MW: | 342.7 D |
From 68.00€
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Vesnarinone
Item number: Cay23489-25
Vesnarinone is an inhibitor of phosphodiesterase 3 (PDE3, IC50s = 10.7 and 13.2 µM for PDE3A and PDE3B, respectively). It also inhibits ether-a-go-go-related gene 1 (ERG1) channels (IC50 = 1.1 µM in HEK293T cells expressing human ERG1). Vesnarinone (3-300 µM) increases contractile tension in isolated ventricular...
| Keywords: | OPC 8212, 6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone |
| Application: | PDE3 inhibitor |
| CAS | 81840-15-5 |
| MW: | 395.5 D |
From 43.00€
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