7 products were found matching "Cay13487"!

PB-22 N-(5-hydroxypentyl) metabolite is an expected metabolite of PB-22 (Cay-14096), based on the metabolism of JWH 018 (Cay-10900). PB-22 is a synthetic cannabinoid that is structurally analogous to the potent aminoalkylindoles, like JWH 018. The physiological and toxicological properties of this compound have not...

Tenofovir is an analog of adenosine monophosphate that has antiviral activity. It is converted by cellular enzymes to tenofovir diphosphate, an obligate chain terminator that inhibits the activity of HIV reverse transcriptase and hepatitis B virus polymerase. Tenofovir diphosphate is a weak inhibitor of mammalian...

Desmopressin is a synthetic version of the endogenous antidiuretic hormone arginine vasopressin (AVP). Compared to AVP, the first amino acid of desmopressin has been deaminated, and the arginine at the eighth position is in the dextrorotatory rather than the levorotatory form. Desmopressin acts as an agonist at...

Nafamostat is a serine protease inhibitor that is capable of inhibiting trypsin (a digestive system protease, Ki = 15 nM), tryptase (a mast cell protease, Ki = 95.3 pM), and additional proteases in the coagulation cascade including thrombin (Ki = 0.84 µM). In a mouse model of allergic asthma, a dose of 300 mg/kg...

EDG-6 is a member of the endothelial differentiation gene (EDG) G protein-coupled receptor family and is a receptor for sphingosine 1-phosphate (S1P). Binding of S1P to EDG-6 activates Erk, leading to the activation of the transcription factor Elk1 and thus the mitogen-activated protein kinase (MAPK) signal...

LSD1, the first known lysine-specific histone demethylase, is an 886 amino acid nuclear protein belonging to flavin monoamine oxidase family. It contains a SWIRM domain, a FAD-binding motif and an amine oxidase domaine. This protein is ubiquitously expressed and is a component of several histone deacetylase...

Calcitonin is a 32-amino acid peptide hormone that lowers blood calcium levels and inhibits bone resorption. The amino acid sequence of eel calcitonin varies from salmon (Cay-24410) and human (Cay-24409) calcitonin at 3 and 16 positions, respectively. Calcitonin (eel) binds to calcitonin receptor 2 (CTR2) with...