4 products were found matching "Cay13452-%25"!
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PGDM
Item number: Cay13454-25
Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily...
| Keywords: | Prostaglandin D Metabolite, 9alpha,11beta-dihydroxy-15-oxo-13,14-dihydro-2,3,18,19-tetranor-prostan-1,20-dioic acid |
| Application: | Biomarker for PGD2 |
| CAS | 133161-96-3 |
| MW: | 328.4 D |
From 237.00€
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IWP-4
Item number: Cay13954-25
IWP-4 is an inhibitor of Wnt production that impairs Wnt pathway activity in vitro with an IC50 value of 25 nM. IWP-4 inactivates Porcupine, a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. At 5 µM, IWP-4 has been shown to...
| Keywords: | Inhibitor of Wnt Production-4,... |
| Application: | Wnt production inhibitor, Porcupine inactivator |
| CAS | 686772-17-8 |
| MW: | 496.6 D |
From 48.00€
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Donepezil
Item number: Cay13245-25
Donepezil is an inhibitor of acetylcholinesterase (AChE, IC50 = 6.7 nM). It is selective for AChE over butyrylcholinesterase (BChE, IC50 = 988 nM). Donepezil (0.1 and 1 µM) inhibits the production of nitric oxide (NO) and TNF-alpha induced by oligomeric amyloid-beta (1-42) (AbetaO1-42) in primary rat microglial...
| Keywords: | Aricept(R), 2,3-dihydro-5,6-dimethoxy-2[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one |
| Application: | AChE inhibitor |
| CAS | 120014-06-4 |
| MW: | 379.5 D |
From 43.00€
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Prostaglandin J2-d4
Item number: Cay19345-25
Prostaglandin J2-d4 is intended for use as an internal standard for the quantification of prostaglandin J2 (Cay-18500) by GC- or LC-MS. Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ2 inhibits platelet...
| Keywords: | PGJ2-d4, (Z)-7-((1S,5R)-5-((S,E)-3-hydroxyoct-1-en-1-yl)-4-oxocyclopent-2-en-1-yl)hept-5-enoic-3,3,4,4-d4 acid |
| Application: | GC-MS, LC-MS, internal standard |
| CAS | 2738376-80-0 |
| MW: | 338.5 D |
From 131.00€
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