- Search results for Cay13382-%25
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11 products were found matching "Cay13382-%25"!
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Item number: Cay13338-25
The Src family of proto-oncogenic kinases include nine mammalian non-receptor tyrosine kinases that are involved in intracellular signaling and are often relevant to carcinogenesis. SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). It weakly...
Keywords: | 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
Application: | Src kinase inhibitor |
CAS | 330161-87-0 |
MW: | 371.5 D |
From 32.00€
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Item number: Cay13308-25
DNA-dependent protein kinase (DNA-PK) binds to strand breaks produced during normal cellular processes or in response to genotoxic stresses, such as ionizing radiation, targeting substrates that facilitate DNA repair. NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK (IC50 = 230...
Keywords: | DNA-PK Inhibitor II, LY293646, 2-(4-morpholinyl)-4H-naphtho[1,2-b]pyran-4-one |
Application: | DNA-PK inhibitor |
CAS | 154447-35-5 |
MW: | 281.3 D |
From 109.00€
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Item number: Cay13358-25
N-Methyl-D-aspartate (NMDA) receptors are Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. CAY10608 is a propanolamine that potently, selectively, and non-competitively antagonizes the NR2B subunit of NMDA receptors (IC50 =...
Keywords: | N-[4-[(2S)-3-[[2-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropoxy]phenyl]-methanesulfonamide |
Application: | NMDA receptor NR2B subunit antagonist |
CAS | 457897-92-6 |
MW: | 433.4 D |
From 52.00€
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Item number: Cay13318-25
KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII, IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).Formal Name:...
Keywords: | 5-isoquinolinesulfonic acid,... |
Application: | CAMKII inhibitor |
CAS | 127191-97-3 |
MW: | 721.9 D |
From 66.00€
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Item number: Cay13883-25
Prostaglandin F2alpha-1-glyceryl ester-d5 (PGF2alpha-1-glyceryl ester-d5) is intended for use as an internal standard for the quantification of PGF2alpha-1-glyceryl ester by GC- or LC-MS. 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid...
Keywords: | PGF2alpha-1-glyceryl ester-d5, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester-d5 |
Application: | Bioactive Lipid Assays |
MW: | 433.6 D |
From 84.00€
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Item number: Cay21338-25
Methacycline is a tetracycline-class antibiotic that is active against a wide range of Gram-positive and Gram-negative organisms. It is readily absorbed from the gastrointestinal tract and reaches a maximum concentration at about the fourth hour, declining to a negligible amount in about 24 hours. It is more active...
Keywords: | 6-methylene Oxytetracycline, Rondomycin,... |
Application: | Antibiotic, Antibacterial, Protein biosynthesis inhibitor |
CAS | 3963-95-9 |
MW: | 478.9 D |
From 43.00€
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Item number: Cay14338-25
Acridine orange is a cell-permeable, nucleic acid-selective fluorescent cationic dye useful for cell cycle determination and detection of cellular autophagy. It exhibits excitation/emission spectra of 502/525, 460/650, and 475/590 nm when bound to dsDNA, bound to ssDNA or RNA, and under acidic conditions,...
Keywords: | C.I. 46005B, NSC 194350, N3,N3,N6,N6-tetramethyl-3,6-acridinediamine |
Application: | Cell cycle determination |
CAS | 494-38-2 |
MW: | 265.4 D |
From 84.00€
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Item number: Cay13838-25
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3, important second messengers that modulate the activity of downstream targets Akt and mTOR. Aberrant PI3K/Akt is associated with many human cancers. CAY10626 is a...
Keywords: | N-[2-(dimethylamino)ethyl]-N-methyl-4-[[[[4-[4-(4-morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]ph... |
Application: | PI3K inhibitor |
CAS | 1202884-94-3 |
MW: | 624.7 D |
From 141.00€
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Item number: Cay16338-25
SR 11302 is a synthetic retinoid that inhibits AP-1 activity without activating transcription through RARE. It significantly suppresses both AP-1 activation and phorbol ester-induced papilloma formation in mice when applied topically (0.1 µM). SR 11302 is used to elucidate the role of AP-1 in various signaling...
Keywords: | (2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid |
Application: | AP-1 inhibitor |
CAS | 160162-42-5 |
MW: | 376.5 D |
From 60.00€
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Item number: Cay15338-25
JIB-04 is a pyridine hydrazone that broadly inhibits Jumonji histone demethylases (IC50s values = 230, 340, 435, 445, 855 and 1,100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3, and JMJD2C, respectively). It does not inhibit histone deacetylases and has minimal effect on the iron-containing enzymes methylcytosine...
Keywords: | JHDM Inhibitor VII, NSC 693627, phenyl-2-pyridinyl-methanone, (E,E)-2-(5-chloro-2-pyridinyl)hydrazone |
Application: | Jumonji histone demethylase inhibitor |
CAS | 199596-05-9 |
MW: | 308.8 D |
From 109.00€
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Item number: Cay31382-25
Dihydro K22 is a derivative of the antiviral agent K22 (Cay-31578).Formal Name: N-[2-[4-(4-bromophenyl)-4-hydroxy-1-piperidinyl]-2-oxo-1-(phenylmethyl)ethyl]-benzamide. CAS Number: 2926907-58-4. Molecular Formula: C27H27BrN2O3. Formula Weight: 507.4. Purity: >98%. Formulation: (Request formulation change), A...
Keywords: | N-(1-(4-(4-bromophenyl)-4-hydroxypiperidin-1-yl)-1-oxo-3-phenylpropan-2-yl)benzamide |
Application: | Antiviral agent K22 derivative |
CAS | 2926907-58-4 |
MW: | 507.4 D |
From 92.00€
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