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CAY10621
Item number: Cay13371-25
CAY10621 is an inhibitor of sphingosine kinase 1 (SPHK1, IC50 = 3.3 µM). It is selective for SPHK1 over SPHK2 at 10 µM and PKC at concentrations less than 100 µM. CAY10621 inhibits SPHK1 activity by 70% in U937 cells when used at a concentration of 5 µM.Formal Name:...
| Keywords: | SKI 5C, SPHK1 Inhibitor 5C, (4S)-2,2-dimethyl-4-(1-oxo-2-hexadecyn-1-yl)-3-oxazolidinecarboxylic acid, 1,1-dimethylethyl... |
| Application: | SPHK 1 inhibitor |
| CAS | 120005-55-2 |
| MW: | 435.6 D |
From 38.00€
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5-bromo-3-phenyl Salicylic Acid
Item number: Cay13379-25
The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases (HSDs), with AKR1C1 being a 20alpha-HSD and the other three being 3alpha-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin,...
| Keywords: | 5-bromo-2-hydroxy-[1,1'-biphenyl]-3-carboxylic acid |
| Application: | AKR1C1 inhibitor |
| CAS | 99514-99-5 |
| MW: | 293.1 D |
From 74.00€
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