4 products were found matching "Cay13365-%25"!

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Item number: Cay13665-25

Microsomal prostaglandin E2 synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever, and pain. 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs), which are pro-inflammatory mediators. YS-121 is a dual inhibitor of...

Keywords:	2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-octanoic acid
Application:	mPGES-1/5-LO inhibitor
CAS	916482-17-2
MW:	408 D

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tetranor-PGAM

Item number: Cay13369-25

Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as...

Keywords:	tetranor-Prostaglandin A Metabolite, 5R-(2-carboxyethyl)-epsilon,4-dioxo-2-cyclopentene-1S-octanoic acid
Application:	Prostaglandin studies
CAS	52510-53-9
MW:	310.3 D

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tetranor-PGJM

Item number: Cay13363-25

Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. tetranor-PGDM is an abundant urinary metabolite of PGD2 that is detectable both in...

Keywords:	tetranor-PGJ Metabolite, 8-((1R,2S)-2-(2-carboxyethyl)-5-oxocyclopent-3-en-1-yl)-6-oxooctanoic acid
Application:	Lipid studies
CAS	1352751-83-7
MW:	310.3 D

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(±)17(18)-EpETE methyl ester

Item number: Cay13367-25

(±)17(18)-EpETE methyl ester is an analog of the eicosapentaenoic acid (EPA) metabolite (±)17(18)-EpETE (Cay-50861) that is more lipid soluble.Formal Name: (±)17,18-epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid, methyl ester. CAS Number: 141339-46-0. Synonyms: (±)17,18-EEQ methyl ester, (±)17,18-epoxy Eicosatetraenoic...

Keywords:	(±)17,18-EEQ methyl ester, (±)17,18-epoxy Eicosatetraenoic Acid methyl ester,...
Application:	More lipid soluble methyl ester
CAS	141339-46-0
MW:	332.5 D

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