Lignoceric acid is a 24-carbon saturated (24:0) fatty acid. In mammals, it is synthesized during brain development and is found in cerebrosides. The deficient peroxisomal oxidation of very-long-chain fatty acids, including lignoceric acid, contributes to certain syndromes, including Zellweger cerebro-hepato-renal...

Zearalenone is a mycotoxin that has been found in Fusarium and has estrogenic activities. It binds to human estrogen receptor alpha (ERalpha) and ERbeta (IC50s = 9 and 5.8 nM, respectively). Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male...

E-64d is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases and has diverse biological activities. It is a synthetic analog of E-64 (Cay-10007963) and prodrug form of E-64c (Cay-10007964) that inhibits calpain and the cysteine proteases cathepsins F, -K, -B, -H, and...