- Search results for Cay13343-%25
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
8 products were found matching "Cay13343-%25"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay13340-25
As a cofactor of more than 300 enzymes, zinc is integral for a wide variety of cellular processes that affect most biological functions. Most notably, its bioavailability is important to the regulation of apoptosis, cell proliferation, and differentiation. TPEN is a cell permeant metal ion chelator that is used in...
Keywords: | TPEDA, N,N,N',N'-tetrakis(2-pyridinylmethyl)-1,2-ethanediamine |
Application: | Metal ion chelator |
CAS | 16858-02-9 |
MW: | 424.6 D |
From 23.00€
*
Item number: Cay13342-25
SU 5416 is a tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR2, FLK1/KDR) and a suppressor of tumor vascularization, preventing the growth of multiple tumor types. In addition to inhibiting VEGFR2 (IC50 = 1 µM), SU 5416 also inhibits PDGFR (IC50 = 20 µM),...
Keywords: | NSC 696819, Semaxinib, Sugen 5416, VEGFR 2 Kinase Inhibitor,... |
Application: | Tyrosine kinase inhibitor |
CAS | 204005-46-9 |
MW: | 238.3 D |
From 164.00€
*
Item number: Cay13341-25
Transforming growth factor-beta (TGF-beta) signals through a cell surface heteromeric complex involving type I (TGF-beta RI) and type II (TGF-beta RII) receptors. Downstream signal transduction is mediated by the TGF-beta RI kinase domain through the phosphorylation of Smad proteins. LY364947 is a selective...
Keywords: | HTS 466284, TGF-beta RI Kinase Inhibitor, 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline |
Application: | TGFbetaRI inhibitor |
CAS | 396129-53-6 |
MW: | 272.3 D |
From 123.00€
*
Item number: Cay13303-25
Three genes encode dual specificity phosphatases that are Cdc25 homologs. The phosphatases, Cdc25A through C, are proto-oncogenes and are often over-expressed in cancers. NSC 663284 is a potent, cell-permeable, and irreversible inhibitor of all Cdc25 isoforms, with preference for Cdc25A (IC50 = 29, 95, and 89 nM for...
Keywords: | Cdc25 Phosphatase Inhibitor II, DA-3003-1, SPS8I1, 6-chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione |
Application: | Cdc25 inhibitor |
CAS | 383907-43-5 |
MW: | 321.8 D |
From 32.00€
*
Item number: Cay13313-25
IKK-16 is a potent inhibitor of IkappaB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKalpha, IKKbeta, and IKK complex, respectively, in cell-free assays. It is effective in cells and in animals and has been used delineate the role of NF-kappaB signaling in diverse contexts. IKK-16 has also been...
Keywords: | IKK Inhibitor VII, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone,... |
Application: | IkappaB kinase inhibitor |
CAS | 1186195-62-9 |
MW: | 520.1 D |
From 125.00€
*
Item number: Cay13323-25
IM-54 is an indolylmaleimide derivative which, at 1 µM, inhibits necrotic cell death induced by H2O2 in promyelocytic leukemia HL-60 cells. It does not prevent etoposide-induced apoptosis and does not inhibit protein kinase C or S6 kinase 1.Formal Name:...
Keywords: | 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione |
Application: | Necrotic cell death inhibitor |
CAS | 861891-50-1 |
MW: | 325.4 D |
From 42.00€
*
Item number: Cay11343-5
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin B is a nonselective inhibitor of the mitochondrial F1FO ATP synthase. Oligomycin B (1-10 µM) can reduce the rate...
Keywords: | (1S,2'R,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,28R,29S)-22-ethyl-5',6'-dihydro-7,11,14,15-tetrahydrox... |
Application: | Apoptosis inducer |
CAS | 11050-94-5 |
MW: | 805.1 D |
From 54.00€
*
Item number: Cay33431-25
RIPA-56 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1, IC50 = 13 nM). It is selective for RIPK1 over RIPK3 at 10 µM, as well as over a panel of additional kinases at 2 µM. RIPA-56 inhibits Z-VAD-FMK-induced necrosis in HT-29 cells (EC50 = 28 nM). In vivo, RIPA-56 (6 mg/kg) reduces...
Keywords: | N-hydroxy-2,2-dimethyl-N-(phenylmethyl)-butanamide |
Application: | RIPK1 inhibitor |
CAS | 1956370-21-0 |
MW: | 221.3 D |
From 84.00€
*