2 products were found matching "Cay13341-%25"!

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LY364947
LY364947

Item number: Cay13341-25

Transforming growth factor-beta (TGF-beta) signals through a cell surface heteromeric complex involving type I (TGF-beta RI) and type II (TGF-beta RII) receptors. Downstream signal transduction is mediated by the TGF-beta RI kinase domain through the phosphorylation of Smad proteins. LY364947 is a selective...
Keywords: HTS 466284, TGF-beta RI Kinase Inhibitor, 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline
Application: TGFbetaRI inhibitor
CAS 396129-53-6
MW: 272.3 D
From 123.00€ *
Review
Rapamycin
Rapamycin

Item number: Cay13346-1

Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
Keywords: AY 22989, NSC 226080, Wy 090217,...
Application: mTORC1 blocking
CAS 53123-88-9
MW: 914.2 D
From 50.00€ *
Review