4 products were found matching "Cay13321-%25"!
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Fumagillin
Item number: Cay11332-1
Fumagillin is a fungal metabolite that has been found in A. fumigatus and has diverse biological activities. It inhibits methionyl aminopeptidase 2 (METAP2, IC50 = 10 nM). Fumagillin (10 ng/ml) inhibits tube formation in a rat blood vessel organ culture assay. It inhibits E. cuniculi replication in isolated rabbit...
| Keywords: | Amebacilin, NSC 9168, 2E,4E,6E,8E-decatetraenedioic acid,... |
| Application: | Angiogenesis inhibitor, metabolic studies |
| CAS | 23110-15-8 |
| MW: | 458.6 D |
From 129.00€
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bpV(phen) (potassium hydrate)
Item number: Cay13331-25
bpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 38 nM). It also inhibits the vascular endothelial PTP, PTP-beta (IC50 = 343 nM), and PTP-1beta (IC50 = 920 nM). At 0.1 mM, bpV(phen) inhibits SH2 domain-containing...
| Keywords: | Bisperoxovanadium(phen), Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V),... |
| Application: | PTP inhibitor |
| CAS | 171202-16-7 |
| MW: | 404.3 D |
From 49.00€
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LY364947
Item number: Cay13341-25
Transforming growth factor-beta (TGF-beta) signals through a cell surface heteromeric complex involving type I (TGF-beta RI) and type II (TGF-beta RII) receptors. Downstream signal transduction is mediated by the TGF-beta RI kinase domain through the phosphorylation of Smad proteins. LY364947 is a selective...
| Keywords: | HTS 466284, TGF-beta RI Kinase Inhibitor, 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline |
| Application: | TGFbetaRI inhibitor |
| CAS | 396129-53-6 |
| MW: | 272.3 D |
From 123.00€
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CAY10621
Item number: Cay13371-25
CAY10621 is an inhibitor of sphingosine kinase 1 (SPHK1, IC50 = 3.3 µM). It is selective for SPHK1 over SPHK2 at 10 µM and PKC at concentrations less than 100 µM. CAY10621 inhibits SPHK1 activity by 70% in U937 cells when used at a concentration of 5 µM.Formal Name:...
| Keywords: | SKI 5C, SPHK1 Inhibitor 5C, (4S)-2,2-dimethyl-4-(1-oxo-2-hexadecyn-1-yl)-3-oxazolidinecarboxylic acid, 1,1-dimethylethyl... |
| Application: | SPHK 1 inhibitor |
| CAS | 120005-55-2 |
| MW: | 435.6 D |
From 38.00€
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