- Search results for Cay13318
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3 products were found matching "Cay13318"!
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Item number: Cay13318-5
KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII, IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).Formal Name:...
Keywords: | 5-isoquinolinesulfonic acid,... |
Application: | CAMKII inhibitor |
CAS | 127191-97-3 |
MW: | 721.9 D |
From 66.00€
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Item number: Cay13118-5
Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces...
Keywords: | 1,1-Dimethylbiguanide hydrochloride, N,N-dimethyl-imidodicarbonimidic diamide, monohydrochloride |
Application: | AMPK activator |
CAS | 1115-70-4 |
MW: | 165.6 D |
From 31.00€
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Item number: Cay13188-250
Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin and potentiates the procoagulation process by activating factors V, VIII, XI, and XIII. Conversely, thrombin aids the anticoagulant process by activating protein C. Activated protein C inhibits activated factors V and VIII...
Keywords: | Activated Factor II [IIa] |
Application: | Thrombin mediated signaling studies |
MW: | 38 kD |
From 205.00€
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