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Bisindolylmaleimide IV
Item number: Cay13299-25
Bisindolylmaleimide IV (BIM IV) is a cell permeable inhibitor of protein kinase C (PKC) with IC50 values reported to range from 0.10 to 0.55 µM. BIM IV was designed to be more discriminative than its parent compound, the non-selective PKC inhibitor, staurosporine (Cay-81590). However, BIM IV also inhibits protein...
| Keywords: | Arcyriarubin A, BIM IV, 3,4-di-1H-indol-3-yl-1H-pyrrole-2,5-dione |
| Application: | PKC inhibitor |
| CAS | 119139-23-0 |
| MW: | 327.3 D |
From 72.00€
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PD 158780
Item number: Cay13329-25
PD 158780 is a pyridopyrimidine derivative that reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor tyrosine kinase superfamily: EGFR (IC50 = 8 µM), ErbB2 (IC50 = 49 nM), ErbB3, and ErbB4 (IC50 = 52 nM). It does not inhibit PDGF or FGF-mediated tyrosine phosphorylation. At 0.5...
| Keywords: | N4-(3-bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine |
| Application: | EGFR / erbB2 / erbB3 / erbB4 inhibitor |
| CAS | 171179-06-9 |
| MW: | 330.2 D |
From 50.00€
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