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Item number: Cay13295-25

HNHA is a cell-permeable inhibitor of histone deacetylase (HDAC) activity (IC50 = 100 nM). In human fibrosarcoma HT1080 cells, it induces histone hyperacetylation and p21 transcription with concomitant inhibition of cell cycle progression (IC50 ~7.5 µM). HNHA is at least as effective as SAHA in inhibiting tumor...

Keywords:	Histone Deacetylase Inhibitor VI, N-hydroxy-7-(2-naphthalenylthio)-heptanamide
Application:	HDAC inhibitor
CAS	926908-04-5
MW:	303.4 D

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