- Search results for Cay13295
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
10 products were found matching "Cay13295"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay13295-5
HNHA is a cell-permeable inhibitor of histone deacetylase (HDAC) activity (IC50 = 100 nM). In human fibrosarcoma HT1080 cells, it induces histone hyperacetylation and p21 transcription with concomitant inhibition of cell cycle progression (IC50 ~7.5 µM). HNHA is at least as effective as SAHA in inhibiting tumor...
Keywords: | Histone Deacetylase Inhibitor VI, N-hydroxy-7-(2-naphthalenylthio)-heptanamide |
Application: | HDAC inhibitor |
CAS | 926908-04-5 |
MW: | 303.4 D |
From 114.00€
*
Item number: Cay11329-5
Cytochalasin C is an actin polymerization inhibitor and fungal metabolite that has been found in C. globosum. It inhibits actin polymerization when used at a concentration of 10 µM. Cytochalasin C is cytotoxic to HeLa cells (IC50 = 99%. Formulation: (Request formulation change), A powder. Solubility: DMF: soluble,...
Keywords: | (3S,3aR,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(acetyloxy)-3,3a,6,6a,9,10,12,15-octahydro-6,12-dihydroxy-4,5,10,12-tetramethyl... |
Application: | Actin polymerization inhibitor |
CAS | 22144-76-9 |
MW: | 507.6 D |
From 130.00€
*
Item number: Cay13299-5
Bisindolylmaleimide IV (BIM IV) is a cell permeable inhibitor of protein kinase C (PKC) with IC50 values reported to range from 0.10 to 0.55 µM. BIM IV was designed to be more discriminative than its parent compound, the non-selective PKC inhibitor, staurosporine (Cay-81590). However, BIM IV also inhibits protein...
Keywords: | Arcyriarubin A, BIM IV, 3,4-di-1H-indol-3-yl-1H-pyrrole-2,5-dione |
Application: | PKC inhibitor |
CAS | 119139-23-0 |
MW: | 327.3 D |
From 72.00€
*
Item number: Cay13229-5
thio-p-Toluamide is a cyclic thioamide building block used in drug discovery chemistry.Formal Name: 4-methyl-benzenecarbothioamide. CAS Number: 2362-62-1. Synonyms: 4-Methylbenzenethioamide. Molecular Formula: C8H9NS. Formula Weight: 151.2. Purity: >98%. Formulation: (Request formulation change), A crystalline...
Keywords: | 4-Methylbenzenethioamide, 4-methyl-benzenecarbothioamide |
Application: | Drug discovery, Building block |
CAS | 2362-62-1 |
MW: | 151.2 D |
From 23.00€
*
Item number: Cay13329-5
PD 158780 is a pyridopyrimidine derivative that reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor tyrosine kinase superfamily: EGFR (IC50 = 8 µM), ErbB2 (IC50 = 49 nM), ErbB3, and ErbB4 (IC50 = 52 nM). It does not inhibit PDGF or FGF-mediated tyrosine phosphorylation. At 0.5...
Keywords: | N4-(3-bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine |
Application: | EGFR / erbB2 / erbB3 / erbB4 inhibitor |
CAS | 171179-06-9 |
MW: | 330.2 D |
From 50.00€
*
Item number: Cay13298-5
Bisindolylmaleimide I (BIM I) is a highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM) that is structurally similar to the poorly selective PKC inhibitor staurosporine (Cay-81590). It acts as a competitive inhibitor for the ATP binding site of PKC and shows high selectivity for PKCalpha,...
Keywords: | BIM I, GF 109203X, Gö 6850, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
Application: | PKC inhibitor |
CAS | 133052-90-1 |
MW: | 412.5 D |
From 115.00€
*
Item number: Cay13297-5
Tyrphostins are a family of protein tyrosine kinase inhibitors originally developed to inhibit cell growth by blocking the activity of certain growth factor receptor kinases (GFRK). The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 µM. It blocks the production of...
Keywords: | Tyrphostin AG-126, 2-[(3-hydroxy-4-nitrophenyl)methylene]-propanedinitrile |
Application: | ERK inhibitor |
CAS | 118409-62-4 |
MW: | 215.2 D |
From 35.00€
*
Item number: Cay13293-5
Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. At higher concentrations,...
Keywords: | 5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-1,3-benzenediol |
Application: | Resveratrol analog, Antioxidant, Selective CYP1A1 inactivator |
CAS | 500-65-2 |
MW: | 258.3 D |
From 119.00€
*
Item number: Cay13291-5
Resveratrol is a natural polyphenolic antioxidant that has anti-cancer properties. CAY10616 is an analog of resveratrol which potently induces apoptosis in promyelocytic leukemia HL-60 cells (IC50 = 40 nM, vs. 50 µM for resveratrol). In addition, CAY10599 induces apoptosis (IC50 = 30 nM) in HL-60R, a cell line...
Keywords: | 5-[(1Z)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxy-phenol |
Application: | Resveratrol analog |
CAS | 586410-08-4 |
MW: | 286.3 D |
From 38.00€
*
Item number: Cay13294-5
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2alpha with an IC50 of 4.2 nM...
Keywords: | N-[[(2S,4R)-1-[2-(2,4-difluorobenzoyl)benzoyl]-4-[(triphenylmethyl)thio]-2-pyrrolidinyl]methyl]-4-[(Z)-(2,4-dioxo-5-thiazo... |
Application: | cPLA2 inhibitor |
CAS | 341973-06-6 |
MW: | 850 D |
From 164.00€
*