6-keto PGE1 is a metabolite isolated after the incubation of PGI2 with rabbit liver microsomes. However, it is not produced in appreciable amounts following IV infusion of PGI2 in humans. 6-keto PGE1 is equipotent with PGI2 as a vasodilator, in most other aspects its activity resembles PGE1.Formal Name:...

Protein S-palmitoylation is the post-translational acylation of proteins and serves to regulate localization, stability, and interaction with associates and substrates. Palmitic acid alkyne is a form of palmitic acid (Cay-10006627) with an omega-terminal alkyne. The terminal alkyne group can be used in linking...

Farnesyl alcohol is an isoprenoid that has been found in aromatic plants and has diverse biological activities. It is an agonist of peroxisome proliferator-activator receptor alpha (PPARalpha) and PPARgamma (EC50s = 5.5 and 28 µM, respectively, in a reporter assay using CV-1 cells) and increases the expression of...

URB447 is a cannabinoid 1 (CB1) receptor antagonist and CB2 receptor agonist. It inhibits the binding of the CB receptor agonist [3H]-WIN 55,212-2 to CHO-K1 cells expressing the human CB2 receptor or rat cerebellar membranes (IC50s = 41 and 313 nM, respectively). URB447 (20 mg/kg) reduces food intake and weight gain...