- Search results for Cay13205
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11 products were found matching "Cay13205"!
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Item number: Cay13200-5
G-418 is an aminoglycoside antibiotic. It is active against T. thermophila (IC50 = 10 µM). It inhibits the 80S ribosome and protein elongation during translation in a cell-free assay when used at a concentration of 2 nM. G-418 is used in molecular biology as a selective agent in cell lines or plasmids containing the...
Keywords: | Geneticin,... |
Application: | Antibiotic |
CAS | 108321-42-2 |
MW: | 692.7 D |
From 76.00€
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Item number: Cay13205-5
Halopemide is a potent inhibitor of phospholipase D (PLD), inhibiting human PLD1 and PLD2 in vitro (IC50 = 220 and 310 nM, respectively) and PLD activity in cells. Previously, halopemide has been found to inhibit dopamine receptors and was evaluated as a neuroleptic agent.Formal Name:...
Keywords: | NSC 354856, R34301, N-[2-[4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-ethyl]-4-fluoro-benzamide |
Application: | PLD inhibitor |
CAS | 59831-65-1 |
MW: | 416.9 D |
From 60.00€
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Item number: Cay11320-5
Citrinin is a mycotoxin that has been found in Monascus and has diverse biological activities. It is active against S. aureus, methicillin-resistant S. aureus (MRSA), rifampicin-resistant S. aureus, and vancomycin-resistant E. faecium (MICs = 1.95, 3.9, 0.97, and 7.81 µg/ml, respectively), as well as the pathogenic...
Keywords: | (-)-Citrinin, CTN, NSC 186, (3R,4S)-4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid |
Application: | Apoptosis inducer, mycotoxin |
CAS | 518-75-2 |
MW: | 250.3 D |
From 48.00€
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Item number: Cay13220-5
C-12 NBD cholesterol is a fluorescently tagged cholesterol with the hydrophilic NBD fluorophore attached to the hydrophilic end of cholesterol, separated by a 12-carbon spacer. This design allows the cholesterol to properly orient in membrane bilayers while the fluorescent tag is presented outside of the bilayer....
Keywords: | 3-C12-NBD Cholesterol,... |
Application: | Bioactive lipid assays |
CAS | 1246303-05-8 |
MW: | 747.1 D |
From 114.00€
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Item number: Cay13207-5
Phospholipase D (PLD) is an enzyme which cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1 and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are...
Keywords: | N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4,5]dec-8-yl)ethyl]-2-naphthalenecarboxamide |
Application: | PLD2 inhibitor |
CAS | 1130067-34-3 |
MW: | 428.5 D |
From 68.00€
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Item number: Cay13206-5
Phospholipase D (PLD) is an enzyme which cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1 and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are...
Keywords: | CAY10593, N-[2-[4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-naphthalenecarboxamide |
Application: | PLD1 inhibitor |
MW: | 463 D |
From 50.00€
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Item number: Cay13208-5
Mirin is an inhibitor of the Mre11/Rad50/Nbs1 (MRN) complex, which functions as a DNA damage sensor and activates the DNA repair enzyme ataxia-telangiectasia mutated kinase (ATM). It inhibits phosphorylation of H2AX induced by DNA containing dsDNA breaks (DSBs), indicating decreased ATM activation, with an IC50...
Keywords: | 2-amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone |
Application: | MRN complex inhibitor |
CAS | 299953-00-7 |
MW: | 220.3 D |
From 60.00€
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Item number: Cay13203-5
Agomelatine is an agonist of melatonin (MT) receptors and a derivative of melatonin (Cay-14427). It binds to MT1 and MT2 receptors (Kis = 0.14 and 0.41 nM, respectively) and has an EC50 value of 0.1 nM in a [35S]GTPgammaS binding assay using CHO cells expressing MT2 receptors. Agomelatine is also an antagonist of...
Keywords: | S20098, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-acetamide |
Application: | Melatonin analog |
CAS | 138112-76-2 |
MW: | 243.3 D |
From 102.00€
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Item number: Cay13209-5
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Keywords: | C18-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octadecanamide |
Application: | Bioactive lipid assays |
CAS | 479050-96-9 |
MW: | 367.6 D |
From 53.00€
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Item number: Cay13202-5
Daidzin is an isoflavone that occurs naturally in some plants, including soy and kudzu root. Like other isoflavones, daidzin has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities. Daidzin directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic...
Keywords: | NPI 031D, Daidzoside, 7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
Application: | ALDH2 inhibitor |
CAS | 552-66-9 |
MW: | 416.4 D |
From 52.00€
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Item number: Cay13201-5
N-3-oxo-pentanoyl-L-Homoserine lactone is a chain-shortened derivative of the bacterial quorum sensing signaling molecule N-3-oxo-octanoyl-L-homoserine lactone (Cay-10011206). It inhibits binding of the autoinducer N-3-oxo-hexanoyl homoserine lactone to E. coli containing the transcription factor LuxR when used at a...
Keywords: | 3-oxo-C5-HSL, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-pentanamide |
Application: | Bacterial quorum-sensing signaling molecule |
CAS | 148433-21-0 |
MW: | 199.2 D |
From 43.00€
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