- Search results for Cay13187-%25
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5 products were found matching "Cay13187-%25"!
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Item number: Cay13185-25
17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. 17(S)-HpDHA is generally reduced to 17(S)-HDHA (Cay-10009799), a compound that serves as a precursor to 17(S)-resolvins. 17(S)-HDHA has been shown to inhibit TNF-alpha-induced...
Keywords: | 17(S)-HpDoHE, 17(S)-hydroperoxy Docosahexaenoic Acid, 17S-hydroperoxy-4E,7Z,10Z,13Z,15Z,19Z-docosahexaenoic acid |
Application: | Bioactive lipid assays |
CAS | 123673-33-6 |
MW: | 360.5 D |
From 173.00€
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Item number: Cay13182-25
SU 5402 is an inhibitor of the tyrosine kinase domains of VEGFR2, FGFR1, and PDGFRbeta (IC50s = 0.02, 0.03, and 0.51 µM, respectively). It is much less effective against other receptor tyrosine kinases. SU 5402 is commonly used to evaluate the role of FGFR1 in cellular functions.Formal Name:...
Keywords: | 2-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid |
Application: | FGFR1 /?VEGFR2 inhibitor |
CAS | 215543-92-3 |
MW: | 296.3 D |
From 32.00€
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Item number: Cay13184-25
Equol is a nonsteroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora. The estrogen receptor (ER) binding activity of the naturally occurring (S)-enantiomer demonstrates greater affinity toward ERbeta while the (R)-enantiomer demonstrates greater...
Keywords: | 3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol |
Application: | Estrogen receptor agonist |
CAS | 94105-90-5 |
MW: | 242.3 D |
From 44.00€
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Item number: Cay13871-25
TAK-242 is an antagonist of toll-like receptor 4 (TLR4) with an IC50 value of 0.68 µM in a secreted alkaline phosphatase (SEAP) assay. It selectively binds to TLR4 over TLR1-3 and TLR5-10 when used at a concentration of 100 nM. TAK-242 (1 µM) prevents the interaction of TLR4 with its adaptor proteins TIRAP or TRAM...
Keywords: | Resatorvid, 6R-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid, ethyl ester |
Application: | TLR4 adaptor binding inhibitor |
CAS | 243984-11-4 |
MW: | 361.8 D |
From 98.00€
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Item number: Cay13107-50
Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase). Presumably through these actions, it blocks the activation of T cells by allogeneic dendritic cells (IC50 = 0.55 nM) without affecting dendritic cells. Moreover,...
Keywords: | Elidel, SDZ-ASM 981,... |
Application: | Calcineurin inhibitor |
CAS | 137071-32-0 |
MW: | 810.5 D |
From 35.00€
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