- Search results for Cay13179-%25
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
5 products were found matching "Cay13179-%25"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay13172-25
Histone deacetylase (HDAC) inhibitors hyperacetylate histones and increase transcriptional activity in selected genes. Importantly, HDAC inhibitors induce apoptosis in some cancer cells and show promise in the treatment of certain forms of cancer. CBHA is a potent HDAC inhibitor, exhibiting ID50 values of 0.01 and...
Keywords: | Histone Deacetylase Inhibitor II, m-Carboxycinnamic Acid bis-Hydroxamide,... |
Application: | HDAC inhibitor |
CAS | 174664-65-4 |
MW: | 222.2 D |
From 110.00€
*
Item number: Cay13174-25
M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1 (IC50s = 88 and 249 nM, respectively). M 344 enhances the sensitivity of human squamous carcinoma cells to radiation...
Keywords: | D237, Histone Deacetylase Inhibitor III, MS 344, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide |
Application: | HDAC inhibitor |
CAS | 251456-60-7 |
MW: | 307.4 D |
From 88.00€
*
Item number: Cay13139-25
Imatinib is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit. It inhibits ligand-stimulated autophosphorylation of PDGFR and c-Kit (IC50s = ~0.3 and ~0.1 µM, respectively). Imatinib inhibits the proliferation of Bcr-Abl-dependent R10(-) cells (IC50s = ~35-40 nM) and HMC-1 cells...
Keywords: | CGP57148B, STI-571,... |
Application: | Tyrosine kinase inhibitor |
CAS | 220127-57-1 |
MW: | 589.7 D |
From 40.00€
*
Item number: Cay13109-25
Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directly and selectively inhibits casein kinase II (IC50 = 0.89 µM)....
Keywords: | Archin, Frangulic Acid, NSC 408120, NSC 622947, Schuttgelb, 1,3,8-trihydroxy-6-methyl-9,10-anthracenedione |
Application: | CK2 inhibitor |
CAS | 518-82-1 |
MW: | 270.2 D |
From 40.00€
*
Item number: Cay19173-25
XMD8-92 is an ERK5 inhibitor (Kd = 80 nM) that less potently inhibits DCAMKL2, TNK1, and Plk4 (Kds = 190, 890, and 600 nM, respectively) in a panel of 402 kinases. It blocks ERK5 autophosphorylation, ERK5-mediated phosphorylation of promyelocytic leukemia protein (PML), and PML-dependent activation of p21. XMD8-92...
Keywords: | 2-[[2-ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
Application: | ERK5 inhibitor |
CAS | 1234480-50-2 |
MW: | 474.6 D |
From 43.00€
*