- Search results for Cay13178-%25
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5 products were found matching "Cay13178-%25"!
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Item number: Cay13172-25
Histone deacetylase (HDAC) inhibitors hyperacetylate histones and increase transcriptional activity in selected genes. Importantly, HDAC inhibitors induce apoptosis in some cancer cells and show promise in the treatment of certain forms of cancer. CBHA is a potent HDAC inhibitor, exhibiting ID50 values of 0.01 and...
Keywords: | Histone Deacetylase Inhibitor II, m-Carboxycinnamic Acid bis-Hydroxamide,... |
Application: | HDAC inhibitor |
CAS | 174664-65-4 |
MW: | 222.2 D |
From 110.00€
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Item number: Cay13174-25
M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1 (IC50s = 88 and 249 nM, respectively). M 344 enhances the sensitivity of human squamous carcinoma cells to radiation...
Keywords: | D237, Histone Deacetylase Inhibitor III, MS 344, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide |
Application: | HDAC inhibitor |
CAS | 251456-60-7 |
MW: | 307.4 D |
From 88.00€
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Item number: Cay13871-25
TAK-242 is an antagonist of toll-like receptor 4 (TLR4) with an IC50 value of 0.68 µM in a secreted alkaline phosphatase (SEAP) assay. It selectively binds to TLR4 over TLR1-3 and TLR5-10 when used at a concentration of 100 nM. TAK-242 (1 µM) prevents the interaction of TLR4 with its adaptor proteins TIRAP or TRAM...
Keywords: | Resatorvid, 6R-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid, ethyl ester |
Application: | TLR4 adaptor binding inhibitor |
CAS | 243984-11-4 |
MW: | 361.8 D |
From 98.00€
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Item number: Cay13108-25
VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1beta, and TNF-alpha production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml,...
Keywords: | 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide |
Application: | p38 MAP kinase inhibitor |
CAS | 745833-23-2 |
MW: | 404.3 D |
From 34.00€
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Item number: E-AB-13178.20
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize...
Keywords: | Anti-CYP2D6, Anti-CYP2DL1, Anti-CYPIID6, Anti-Cytochrome P450-DB1, Anti-Cytochrome P450 2D6, Anti-Cholesterol... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 71.00€
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