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M 344
M 344

Item number: Cay13174-10

M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1 (IC50s = 88 and 249 nM, respectively). M 344 enhances the sensitivity of human squamous carcinoma cells to radiation...
Keywords: D237, Histone Deacetylase Inhibitor III, MS 344, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide
Application: HDAC inhibitor
CAS 251456-60-7
MW: 307.4 D
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