6 products were found matching "Cay13169-%25"!
No results were found for the filter!
NSC 23766 (hydrochloride)
Item number: Cay13196-25
Rac1 is a GTPase that is involved in the regulation of the cell cycle, cell-cell adhesion, motility, and differentiation. Rac1 is activated by its interaction with specific guanine nucleotide exchange factors (GEFs). NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs...
| Keywords: | N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine, trihydrochloride |
| Application: | Rac1 inhibitor |
| CAS | 1177865-17-6 |
| MW: | 531 D |
From 44.00€
*
7-epi Maresin 1
Item number: Cay13161-25
7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 (Cay-10878), which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.Formal Name: 7S,14S-dihydroxy-4Z,8E,10E,12Z,16Z,19Z-docosahexaenoic acid. CAS Number: 1268720-66-6. Synonyms: 7(S)-MaR1, 7(S)-Maresin 1. Molecular Formula:...
| Keywords: | 7(S)-MaR1, 7(S)-Maresin 1, 7S,14S-dihydroxy-4Z,8E,10E,12Z,16Z,19Z-docosahexaenoic acid |
| Application: | Inflammation studies |
| CAS | 1268720-66-6 |
| MW: | 360.5 D |
From 104.00€
*
Splitomicin
Item number: Cay13168-25
Sir2p, the product of the SIR2 gene, is a conserved NAD+-dependent histone deacetylase (HDAC) involved in the regulation of the lifespan in yeast. It plays roles in silencing gene expression and negatively regulates the initiation of DNA replication. Splitomicin is a small molecule inhibitor of Sir2p histone...
| Keywords: | 1-Naphthalenepropanoic Acid, 1,2-dihydro-3H-naphtho[2,1-b]pyran-3-one |
| Application: | SIR2p inhibitor |
| CAS | 5690-03-9 |
| MW: | 198.2 D |
From 43.00€
*
(+)-Blebbistatin
Item number: Cay13165-25
(+)-Blebbistatin is the inactive enantiomer of (-)-blebbistatin (Cay-13013), which is a selective inhibitor of non-muscle myosin II ATPases. Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in...
| Keywords: | (R)-Blebbistatin, 1,2,3,3a-tetrahydro-3aR-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one |
| Application: | Non-muscle myosin II ATPase inhibitor |
| CAS | 1177356-70-5 |
| MW: | 292.3 D |
From 50.00€
*
Imatinib (mesylate)
Item number: Cay13139-25
Imatinib is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit. It inhibits ligand-stimulated autophosphorylation of PDGFR and c-Kit (IC50s = ~0.3 and ~0.1 µM, respectively). Imatinib inhibits the proliferation of Bcr-Abl-dependent R10(-) cells (IC50s = ~35-40 nM) and HMC-1 cells...
| Keywords: | CGP57148B, STI-571,... |
| Application: | Tyrosine kinase inhibitor |
| CAS | 220127-57-1 |
| MW: | 589.7 D |
From 40.00€
*
Emodin
Item number: Cay13109-25
Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directly and selectively inhibits casein kinase II (IC50 = 0.89 µM)....
| Keywords: | Archin, Frangulic Acid, NSC 408120, NSC 622947, Schuttgelb, 1,3,8-trihydroxy-6-methyl-9,10-anthracenedione |
| Application: | CK2 inhibitor |
| CAS | 518-82-1 |
| MW: | 270.2 D |
From 40.00€
*