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Gefitinib
Gefitinib

Item number: Cay13166-250

Gefitinib is an EGFR inhibitor (IC50s = 0.023-0.079 µM). It inhibits colony formation of GEO colon, ZR-75-1 and MCF-10A breast, and OVCAR-3 ovarian cancer cell lines in soft agar assays (IC50s = 0.2-0.4 µM). Gefitinib (0.1 to 1 µM) induces apoptosis and inhibits EGFR autophosphorylation in the same cells. In vivo,...
Keywords: ZD 1839, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine
Application: EGFR-TK inhibitor
CAS 184475-35-2
MW: 446.9 D
From 100.00€ *
Review
Gefitinib
Gefitinib

Item number: Cay13166-100

Gefitinib is an EGFR inhibitor (IC50s = 0.023-0.079 µM). It inhibits colony formation of GEO colon, ZR-75-1 and MCF-10A breast, and OVCAR-3 ovarian cancer cell lines in soft agar assays (IC50s = 0.2-0.4 µM). Gefitinib (0.1 to 1 µM) induces apoptosis and inhibits EGFR autophosphorylation in the same cells. In vivo,...
Keywords: ZD 1839, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine
Application: EGFR-TK inhibitor
CAS 184475-35-2
MW: 446.9 D
44.00€ *
Review
Biotin-X-NHS
Biotin-X-NHS

Item number: Cay13316-100

N-Hydroxysuccinimide (NHS) activates carboxylic acid groups (on biotin) to facilitate coupling reactions. Biotin-X-NHS is a compound used to attach biotin to primary amines under alkaline conditions (pH~8-9). For example, lysines on the surface of proteins, including antibodies, are ideal targets for biotinylation...
Keywords: 6-[[5-[(3aS,4S,6aR)-hexhydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-2,5-dioxo-hexanoic acid,...
Application: Biotinylation
CAS 72040-63-2
MW: 454.5 D
From 158.00€ *
Review