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Anacardic Acid | CAS 16611-84-0

ART NR.: Cay13144-1 (1 mg)
Cay13144-5 (5 mg)
Cay13144-10 (10 mg)

Hersteller: Cayman

Datenblatt

Anwendungen: HAT inhibitor

CAS-Nr. : 16611-​84-​0
Suche mit CAS-Nr.

MW: 348 D

Formel: C22H36O3

Reinheit: >98%

Format: crystalline solid

Lagerung: -20°C

Versand: +20°C

Schlagworte: 2-hydroxy-6-pentadecyl-benzoic acid

Cay13144-1

1 mg

17 €

Cay13144-5

5 mg

44 €

Cay13144-10

10 mg

79 €

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Bemerkungen: Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Literature frequently sites and gives the name anacardic acid to the completely-saturated compound (6-pentadecyl salicylic acid). Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (pCAF) with IC50 values of 8.5 and 5 µM, respectively. At 25 µmol/L, anacardic acid suppresses NF-kappaB activation, inhibits IkappaB-alpha phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.

Verwandte Produkte

    Products for: PCAF, KAT2, GCN5 - histone acetyltransferase [EC:2.3.1.48]

    Die Preise verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.





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