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Cay13144-1
CAS: 16611-​84-​0
HAT inhibitor Erklärungen der Abkürzungen ansehen.
Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Literature frequently sites and gives the name anacardic acid to the completely-saturated compound (6-pentadecyl salicylic acid). Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (pCAF) with IC50 values of 8.5 and 5 µM, respectively. At 25 µmol/L, anacardic acid suppresses NF-kappaB activation, inhibits IkappaB-alpha phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.

MW: 348 D
Formula: C22H36O3
Purity: >98%
Cayman
Icon Datasheet
1 mg

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17 €

Cay13144-10
CAS: 16611-​84-​0
HAT inhibitor Erklärungen der Abkürzungen ansehen.
Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Literature frequently sites and gives the name anacardic acid to the completely-saturated compound (6-pentadecyl salicylic acid). Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (pCAF) with IC50 values of 8.5 and 5 µM, respectively. At 25 µmol/L, anacardic acid suppresses NF-kappaB activation, inhibits IkappaB-alpha phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.

MW: 348 D
Formula: C22H36O3
Purity: >98%
Cayman
Icon Datasheet
10 mg

Buy Bulk

79 €

Cay13144-5
CAS: 16611-​84-​0
HAT inhibitor Erklärungen der Abkürzungen ansehen.
Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Literature frequently sites and gives the name anacardic acid to the completely-saturated compound (6-pentadecyl salicylic acid). Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (pCAF) with IC50 values of 8.5 and 5 µM, respectively. At 25 µmol/L, anacardic acid suppresses NF-kappaB activation, inhibits IkappaB-alpha phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.

MW: 348 D
Formula: C22H36O3
Purity: >98%
Cayman
Icon Datasheet
5 mg

Buy Bulk

44 €


 

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