- Search results for Cay13136-%25
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4 products were found matching "Cay13136-%25"!
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Item number: Cay13139-25
Imatinib is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit. It inhibits ligand-stimulated autophosphorylation of PDGFR and c-Kit (IC50s = ~0.3 and ~0.1 µM, respectively). Imatinib inhibits the proliferation of Bcr-Abl-dependent R10(-) cells (IC50s = ~35-40 nM) and HMC-1 cells...
Keywords: | CGP57148B, STI-571,... |
Application: | Tyrosine kinase inhibitor |
CAS | 220127-57-1 |
MW: | 589.7 D |
From 40.00€
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Item number: Cay13186-25
(±)-Blebbistatin is a racemic mixture of (-)-blebbistatin (Cay-13013) and (+)-blebbistatin (Cay-13165), the active and inactive forms, respectively. (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in...
Keywords: | 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one |
Application: | Non-muscle myosin II ATPase inhibitor |
CAS | 674289-55-5 |
MW: | 292.3 D |
From 115.00€
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Item number: Cay13146-25
Histone deacetylase 6 (HDAC6) is a class II HDAC that represses transcription by removing acetyl groups from histones. In addition, HDAC6 deacetylases tubulin, which is important in regulating microtubule stability and function. CAY10603 is a potent and selective inhibitor of HDAC6 (IC50 = 0.002 nM, as compared with...
Keywords: | HDAC 6 inhibitor, Histone Deacetylase Inhibitor VIII,... |
Application: | HDAC6 inhibitor |
CAS | 1045792-66-2 |
MW: | 446.5 D |
From 65.00€
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Item number: Cay13196-25
Rac1 is a GTPase that is involved in the regulation of the cell cycle, cell-cell adhesion, motility, and differentiation. Rac1 is activated by its interaction with specific guanine nucleotide exchange factors (GEFs). NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs...
Keywords: | N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine, trihydrochloride |
Application: | Rac1 inhibitor |
CAS | 1177865-17-6 |
MW: | 531 D |
From 44.00€
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