6 products were found matching "Cay13121"!

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CHIR99021
CHIR99021

Item number: Cay13122-1

CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein kinases, this inhibitor shows greater than 500-fold selectivity for GSK3. CHIR99021 activates glycogen synthesis in CHO-IR cells (EC50 = 0.763...
Keywords: CT 99021,...
Application: GSK3alpha and GSK3beta inhibitor
CAS 252917-06-9
MW: 465.3 D
From 43.00€ *
Review
Sodium Butyrate
Sodium Butyrate

Item number: Cay13121-50

Sodium butyrate is a short-chain fatty acid. It is produced predominately by bacterial fermentation of dietary fiber in the colon but has also been identified in mammalian milk. Sodium butyrate is an inhibitor of histone deacetylase (HDAC, IC50 = 90 µM in a cell-free assay). It induces differentiation, cell cycle...
Keywords: Butyric Acid, butanoic acid, sodium salt
Application: HDAC inhibitor
CAS 156-54-7
MW: 110.1 D
From 43.00€ *
Review
GW 4869 (hydrochloride hydrate)
GW 4869 (hydrochloride hydrate)

Item number: Cay13127-1

Neutral sphingomyelinases mediate the release of ceramide from sphingomyelin in cellular membranes and can be activated by certain stresses. Ceramide can act as a signaling molecule in its own right, or it can be further processed to generate sphingosine (and sphingosine-1-phosphate). GW 4869 is an inhibitor of...
Keywords: 3,3'-(1,4-phenylene)bis[N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-dihydrochloride-2-propenamide
Application: Neutral sphingomyelinase inhibitor
CAS 6823-69-4
MW: 577.5 D
From 44.00€ *
Review
BIX01294 (hydrochloride hydrate)
BIX01294 (hydrochloride hydrate)

Item number: Cay13124-1

The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. BIX01294...
Keywords: 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine,...
Application: G9a HMTase inhibitor
CAS 1808255-64-2
MW: 600 D
From 40.00€ *
Review
BIO
BIO

Item number: Cay13123-1

BIO is a cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3alpha/beta (IC50 = 5 nM). Its specificity has been tested against various cyclin-dependent kinases (CDKs) (IC50s = 83, 300, 320, and 10,000 nM for Cdk5/p25, Cdk2/A,...
Keywords: GSK3 Inhibitor IX, 6-Bromoindirubin-3'-oxime, MLS 2052,...
Application: GSK-3 inhibitor
CAS 667463-62-9
MW: 356.2 D
From 43.00€ *
Review
trans-trismethoxy Resveratrol-d4
trans-trismethoxy Resveratrol-d4

Item number: Cay13129-1

trans-trismethoxy Resveratrol-d4 is intended for use as an internal standard for the quantification of trans-trismethoxy resveratrol (Cay-10188) by GC- or LC-MS. trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities....
Keywords: (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzene diol-d4, 1,3-dimethoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene-2,3,5,6-d4
Application: Standard
CAS 1089051-64-8
MW: 274.4 D
From 66.00€ *
Review