- Search results for Cay13121
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6 products were found matching "Cay13121"!
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Item number: Cay13122-1
CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein kinases, this inhibitor shows greater than 500-fold selectivity for GSK3. CHIR99021 activates glycogen synthesis in CHO-IR cells (EC50 = 0.763...
Keywords: | CT 99021,... |
Application: | GSK3alpha and GSK3beta inhibitor |
CAS | 252917-06-9 |
MW: | 465.3 D |
From 43.00€
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Item number: Cay13121-50
Sodium butyrate is a short-chain fatty acid. It is produced predominately by bacterial fermentation of dietary fiber in the colon but has also been identified in mammalian milk. Sodium butyrate is an inhibitor of histone deacetylase (HDAC, IC50 = 90 µM in a cell-free assay). It induces differentiation, cell cycle...
Keywords: | Butyric Acid, butanoic acid, sodium salt |
Application: | HDAC inhibitor |
CAS | 156-54-7 |
MW: | 110.1 D |
From 43.00€
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Item number: Cay13127-1
Neutral sphingomyelinases mediate the release of ceramide from sphingomyelin in cellular membranes and can be activated by certain stresses. Ceramide can act as a signaling molecule in its own right, or it can be further processed to generate sphingosine (and sphingosine-1-phosphate). GW 4869 is an inhibitor of...
Keywords: | 3,3'-(1,4-phenylene)bis[N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-dihydrochloride-2-propenamide |
Application: | Neutral sphingomyelinase inhibitor |
CAS | 6823-69-4 |
MW: | 577.5 D |
From 44.00€
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Item number: Cay13124-1
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. BIX01294...
Keywords: | 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine,... |
Application: | G9a HMTase inhibitor |
CAS | 1808255-64-2 |
MW: | 600 D |
From 40.00€
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Item number: Cay13123-1
BIO is a cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3alpha/beta (IC50 = 5 nM). Its specificity has been tested against various cyclin-dependent kinases (CDKs) (IC50s = 83, 300, 320, and 10,000 nM for Cdk5/p25, Cdk2/A,...
Keywords: | GSK3 Inhibitor IX, 6-Bromoindirubin-3'-oxime, MLS 2052,... |
Application: | GSK-3 inhibitor |
CAS | 667463-62-9 |
MW: | 356.2 D |
From 43.00€
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Item number: Cay13129-1
trans-trismethoxy Resveratrol-d4 is intended for use as an internal standard for the quantification of trans-trismethoxy resveratrol (Cay-10188) by GC- or LC-MS. trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities....
Keywords: | (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzene diol-d4, 1,3-dimethoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene-2,3,5,6-d4 |
Application: | Standard |
CAS | 1089051-64-8 |
MW: | 274.4 D |
From 66.00€
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