6 products were found matching "Cay13101"!
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13,14-dihydro-15-keto-tetranor Prostaglandin E2
Item number: Cay13101-10
A common metabolic pathway for several prostaglandins (PG), including PGE2, involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the alpha-terminus and oxidation of the terminal omega-carbon...
| Keywords: | 9,15-dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostanoic acid |
| Application: | Metabolic studies |
| CAS | 20675-85-8 |
| MW: | 298.4 D |
From 131.00€
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Gö 6976
Item number: Cay13310-1
Gö 6976 is a nonglycosidic indolocarbazole that inhibits protein kinase C (PKC) with IC50 values of 2.3 and 6.2 nM for PKCalpha and PKCbeta1, respectively. It does not inhibit the activity of PKCdelta, PKCepsilon, or PKCzeta (IC50s > 3 µM), indicating a preference for the Ca2+-dependent subtypes, PKCalpha and...
| Keywords: | PD 406976, 5,6,7,13-tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile |
| Application: | PKCalpha / PKCbeta1 inhibitor |
| CAS | 136194-77-9 |
| MW: | 378.4 D |
From 66.00€
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Streptozotocin
Item number: Cay13104-1
Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. It specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. DNA damage induces activation of poly ADP-ribosylation, depletion of cellular NAD+ and...
| Keywords: | Estreptozocin, NSC 37917, NSC 85998, Streptozocin, STZ, U 9889, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose |
| Application: | Diabetes inducer, NO donor |
| CAS | 18883-66-4 |
| MW: | 265.2 D |
From 32.00€
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MAM2201 N-(5-chloropentyl) analog
Item number: Cay13103-1
MAM2201 (Cay-9001219) is a synthetic cannabinoid (CB) that is closely related, structurally, to AM2201 (Cay-10707), a compound which displays high affinities for both CB receptors. MAM2201 N-(5-chloropentyl) analog (Cay-13103) differs from MAM2201 by having chlorine rather than fluorine on the terminal carbon of the...
| Keywords: | JWH 122 N-(5-chloropentyl) analog, (1-(5-chloropentyl)-1H-indol-3-yl)(4-methylnaphthalen-1-yl)methanone |
| Application: | Analytical reference standard, synthetic cannabinoid analog |
| CAS | 1445578-25-5 |
| MW: | 389.9 D |
From 291.00€
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Skyrin
Item number: Cay13102-1
Skyrin is a fungal metabolite characterized by a bisanthraquinone structure. It interferes with glucagon signaling through adenylate cyclase without binding to the glucagon receptor. At 10 µM, skyrin reduces both glucagon-stimulated cAMP production and glycogenolysis. It does not interfere with epinephrine or...
| Keywords: | Endothianin, Rhodophyscin, 2,2',4,4',5,5'-hexahydroxy-7,7'-dimethyl-[1S,1'-bianthracene]-9,9',10,10'-tetrone |
| Application: | Antioxidant, glucagon antagonist |
| CAS | 602-06-2 |
| MW: | 538.5 D |
245.00€
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Prostaglandin E1
Item number: Cay13010-1
Prostaglandin E1 (PGE1) is a vasoactive prostaglandin and an active metabolite of dihomo-gamma-linolenic acid (DGLA, Cay-90230). It is formed from DGLA by COX-1 and COX-2. PGE1 is an agonist of the PGE2 (Cay-14010) receptor subtypes EP1, EP2, EP3, and EP4, and the IP receptor (Kis = 36, 10, 1.1, 2.1, and 33 nM,...
| Keywords: | Alprostadil, PGE1, 9-oxo-11alpha,15S-dihydroxy-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 745-65-3 |
| MW: | 354.5 D |
From 30.00€
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