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STF-62247
STF-62247

Item number: Cay13084-25

STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM). It significantly reduces the growth rate of tumors formed from VHL-deficient cells in mice. STF-62247...
Keywords: N-(3-methylphenyl)-4-(4-pyridinyl)-2-thiazolamine
Application: Autophagy inducer
CAS 315702-99-9
MW: 267.3 D
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