- Search results for Cay13079
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10 products were found matching "Cay13079"!
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Item number: Cay13907-1
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth...
Keywords: | IL-1beta Converting Enzyme |
Application: | IHC (paraffin), WB |
Host: | Mouse |
Species reactivity: | human |
465.00€
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Item number: Cay17930-25
[3,2-c]Pyrazole-androst-4-en-17beta-ol is a steroidal heterocyclic compound that is classified as a controlled substance in the United States through the Designer Anabolic Steroid Control Act of 2014. This compound is intended for forensic and research purposes only.Formal Name:...
Keywords: | (17beta)-2'H-androsta-2,4-dieno[3,2-c]pyrazol-17-ol |
Application: | Analytical reference standard, Designer anabolic androgenic steroid |
CAS | 929042-39-7 |
MW: | 312.5 D |
From 43.00€
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Item number: Cay17309-5
NG 52 is a tri-substituted purine that binds to the ATP-binding site of yeast cyclin-dependent kinases, inhibiting Cdc28p and Pho85p (IC50s = 7 and 2 µM, respectively). It is ineffective against the yeast kinases Kin28p, Srb10, and Cak1p. NG 52 is cell permeable and inhibits the growth of S. cerevisiae (GI50 = 30...
Keywords: | Compound 52, 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-ethanol |
Application: | Cdc28p / Pho85p inhibitor |
CAS | 212779-48-1 |
MW: | 346.8 D |
From 50.00€
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Item number: Cay13179-500
Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, yielding a free fatty acid and a lysophospholipid as products. There are three broad classes of PLA2, secretory (sPLA2), calcium-dependent cytosolic (cPLA2), and calcium-independent cytosolic (iPLA2), that...
Keywords: | 1,1,1,2,2-pentafluoro-7-phenyl-3-heptanone |
Application: | iPLA2 inhibitor |
CAS | 1071000-98-0 |
MW: | 280.2 D |
From 49.00€
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Item number: Cay13579-100
Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within...
Keywords: | alpha-ethyl-6-[5-[2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[... |
Application: | Tumor growth inhibitor, Antiprotozoal, Coccidiostat |
CAS | 53003-10-4 |
MW: | 751 D |
From 34.00€
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Item number: Cay13979-10
JWH 167 is a synthetic cannabinoid (CB) with moderate affinities for both central CB1 (Ki = 90 nM) and peripheral CB2 (Ki = 159 nM) receptors. Its physiological and toxicological properties are not known. This product is intended for forensic and research purposes.Formal Name:...
Keywords: | 1-(1-pentyl-1H-indol-3-yl)-2-phenyl-ethanone |
Application: | Analytical reference standard, Synthetic cannabinoid |
CAS | 864445-37-4 |
MW: | 305.4 D |
From 276.00€
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Item number: Cay13279-10
Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines (NAEs), including the endocannabinoid arachidonoyl ethanolamide (AEA). PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 µM). It covalently binds FAAH on Ser241 at the catalytic site, resulting in prolonged elevation of AEA...
Keywords: | N-3-pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide |
Application: | FAAH inhibitor |
CAS | 1196109-52-0 |
MW: | 456.5 D |
From 39.00€
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Item number: Cay13379-10
The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases (HSDs), with AKR1C1 being a 20alpha-HSD and the other three being 3alpha-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin,...
Keywords: | 5-bromo-2-hydroxy-[1,1'-biphenyl]-3-carboxylic acid |
Application: | AKR1C1 inhibitor |
CAS | 99514-99-5 |
MW: | 293.1 D |
From 74.00€
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Item number: Cay13679-10
Fluprostenol isopropyl ester (Cay-16769) is a potent F-series prostaglandin receptor agonist that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. 13,14-epoxy Fluprostenol isopropyl ester is an impurity generated in the production of fluprostenol isopropyl ester. This product is a...
Keywords: | 13,14-epoxy Travoprost,... |
Application: | F-series prostaglandin receptor agonist |
CAS | 2557327-99-6 |
MW: | 516.6 D |
From 142.00€
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Item number: Cay19307-5
Pitolisant is a nonimidazole histamine H3 receptor antagonist (Ki = 0.16 nM) and inverse agonist (EC50 = 1.5 nM). It increases the levels of tele-methylhistamine in mouse brain, indicating histaminergic neuron activity, with an ED50 value of 1.6 mg/kg. Pitolisant also increases dopamine and acetylcholine levels in...
Keywords: | BF 2649, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine, monohydrochloride |
Application: | Histamine H3 receptor antagonist / inverse agonist |
CAS | 903576-44-3 |
MW: | 332.3 D |
From 50.00€
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