- Search results for Cay13076-%25
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6 products were found matching "Cay13076-%25"!
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Item number: Cay17036-25
The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine, 5-HT) is mediated by at least seven major 5-HT receptor subtypes. SB-224289 is a potent 5-HT1B inverse agonist (pKi = 8.16) that displays >75-fold selectivity for human 5-HT1B over all other 5-HT receptors. It has been used to study the...
Keywords: | [2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl](2,5,6,7-tetrahydro-1'-methylspiro[3H-furo[2,3-f]indole-... |
Application: | 5-HT1B inverse agonist |
CAS | 180084-26-8 |
MW: | 557.1 D |
From 77.00€
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Item number: Cay10736-25
(±)-WIN 55,212 is a racemic mixture of the cannabinoid (CB) receptor 1 (CB1) and CB2 agonist (+)-WIN 55,212-2 (Cay-10009023) and the CB2 neutral antagonist (-)-WIN 55,212-3 (Cay-12022). It inhibits electrically induced contractions in mouse vas deferens preparations (IC50 = 0.006 µM) and reduces prostaglandin (PG)...
Keywords: | [2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone,... |
Application: | CB receptor agonist |
CAS | 137795-17-6 |
MW: | 522.6 D |
From 56.00€
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Item number: Cay12076-25
The HER family of receptor tyrosine kinases, EGFR, HER2, HER3, and HER4, mediate proliferation, migration, adhesion, differentiation, and survival in many different cell types and have been implicated in the development and progression of a variety of human tumors. Canertinib is an irreversible quinazoline-based HER...
Keywords: | CI-1033, PD 183805, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide,... |
Application: | EGFR tyrosine kinase inhibitor |
CAS | 289499-45-2 |
MW: | 558.9 D |
From 50.00€
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Item number: Cay18076-25
Oxytetracycline is a broad-spectrum tetracycline antibiotic that inhibits protein synthesis in both Gram-positive and Gram-negative bacteria. The features of its biosynthesis often serve as a representative example for understanding the synthesis of other type II polyketides. Oxytetracycline is also used to examine...
Keywords: | NSC 9169, Terramycin,... |
Application: | Antibiotic, Protein synthesis inhibitor |
CAS | 79-57-2 |
MW: | 460.4 D |
From 43.00€
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Item number: Cay13876-25
Alexidine is an alkyl bis(biguanide) antiseptic which has been used in mouthwashes to eliminate plaque forming microorganisms. It binds to lipopolysaccharide and lipoteichoic acid and inhibits fungal phospholipase B (IC50 ~ 250 nM). Alexidine also inhibits the mitochondrial phosphatase PTPMT1 (IC50 = 1.08 µM, in...
Keywords: | N1,N14-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, dihydrochloride |
Application: | Antiseptic |
CAS | 1715-30-6 |
MW: | 581.7 D |
From 43.00€
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Item number: Cay17630-25
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-211 is a carbamate-based...
Keywords: | [4-(1,1-dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]-methanone |
Application: | LYPLA1 / LYPLA2 inhibitor |
CAS | 2205032-89-7 |
MW: | 418.5 D |
From 50.00€
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