Biotin-azide is a form of biotin with a terminal azide group. It is used to add biotin to other molecules that bear either an alkyne group, through click chemistry, or a phosphine group, using Staudinger ligation. Biotin-azide has been commonly used to biotin-tag alkynylated lipids, particularly those associated...

2-Pyridylthioamide is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 2-pyridinecarbothioamide. CAS Number: 5346-38-3. Synonyms: NSC 1606, Picolinic Acid Thioamide. Molecular Formula: C6H6N2S. Formula Weight: 138.2. Purity: >98%. Formulation: (Request formulation change), A crystalline...

MPI-0441138 is a potent inducer of apoptosis and growth inhibition (EC50 = 2 nM for both processes, based on caspase-3 activation and total cellular ATP, respectively) in T47D and HCT116 cells. MPI-0441138 has excellent blood brain barrier penetration and is effective in mouse xenograft cancer models.Formal Name:...

gamma-Glutamyl transferase (GGT) is involved in the transfer of amino acids across the plasma membrane as well as in glutathione metabolism. Serum GGT activity is commonly used as a marker of liver dysfunction and alcohol abuse. It is also useful as a biomarker of type 2 diabetes and cardiovascular disease. OU749 is...

Sphingosine kinase (SPHK) is an important enzyme in the sphingolipid metabolic pathway. SPHKs phosphorylate D-erythro-sphingosine to yield sphingosine-1-phosphate (S1P). To date two isoforms of SPHK, SPHK1 and SPHK2, have been identified & characterized from mammalian cells. Among them, SPHK1 has been implicated to...