2 products were found matching "Cay13031"!
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SB-431542 (hydrate)
Item number: Cay13031-25
SB-431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. SB-431542 specifically blocks Smad signaling, reducing gene...
| Keywords: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide, hydrate |
| Application: | ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor |
| MW: | 384.4 D |
From 43.00€
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NSC 663284
Item number: Cay13303-1
Three genes encode dual specificity phosphatases that are Cdc25 homologs. The phosphatases, Cdc25A through C, are proto-oncogenes and are often over-expressed in cancers. NSC 663284 is a potent, cell-permeable, and irreversible inhibitor of all Cdc25 isoforms, with preference for Cdc25A (IC50 = 29, 95, and 89 nM for...
| Keywords: | Cdc25 Phosphatase Inhibitor II, DA-3003-1, SPS8I1, 6-chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione |
| Application: | Cdc25 inhibitor |
| CAS | 383907-43-5 |
| MW: | 321.8 D |
From 32.00€
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