- Search results for Cay13010
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6 products were found matching "Cay13010"!
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Item number: Cay13010-1
Prostaglandin E1 (PGE1) is a vasoactive prostaglandin and an active metabolite of dihomo-gamma-linolenic acid (DGLA, Cay-90230). It is formed from DGLA by COX-1 and COX-2. PGE1 is an agonist of the PGE2 (Cay-14010) receptor subtypes EP1, EP2, EP3, and EP4, and the IP receptor (Kis = 36, 10, 1.1, 2.1, and 33 nM,...
Keywords: | Alprostadil, PGE1, 9-oxo-11alpha,15S-dihydroxy-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 745-65-3 |
MW: | 354.5 D |
From 30.00€
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Item number: Cay13330-10
1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28...
Keywords: | PP1 Analog II, 1-(1,1-dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Application: | Analog-sensitive kinase inhibitor |
CAS | 221244-14-0 |
MW: | 331.4 D |
From 95.00€
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Item number: Cay11330-10
The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin D is a cell-permeable inhibitor that binds actin filaments, but not actin monomers, to inhibit...
Keywords: | NSC 209835,... |
Application: | Cell-permeable actin polymerization inhibitor |
CAS | 22144-77-0 |
MW: | 507.6 D |
From 83.00€
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Item number: Cay13000-100
Pterostilbene is a polyketide synthase-derived stilbene originally isolated from P. santalinus that has diverse biological activities. It reduces photooxidative leakage induced by the herbicide acifluorfen in C. sativus cotyledon disks when used at a concentration of 30 µg/ml. Pterostilbene (25 and 50 µM) inhibits...
Keywords: | trans-3,5-Dimethoxy-4'-Hydroxystilbene, 3',5'-Dimethoxy-4-Stilbenol, 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl)-phenol |
Application: | Antioxidant |
CAS | 537-42-8 |
MW: | 256.3 D |
From 74.00€
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Item number: Cay11300-100
Methylation of lysine residues in core histones plays a critical role in regulating gene expression. Jumonji domain containing 2D (JMJD2D) catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me 2/3), leading to transcriptional repression and activation, respectively. Like...
Keywords: | KDM4D, JHDM3D, Lysine-specific demethylase 4D, Lysine-specific demethylase 4D, Jumonji domain-containing protein 2D,... |
Application: | Enzyme activity, WB |
Expressed in: | E.coli |
MW: | 42,6 kD |
642.00€
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Item number: Cay13300-10
Bisindolylmaleimide V (BIM V) is a weak inhibitor of protein kinase C (PKC) demonstrating an IC50 value >100 µM. While effectively inactive as a PKC inhibitor, BIM V blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC50 value of 8 µM.Formal Name:...
Keywords: | BIM V, Ro 31-6045, 3,4-di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione |
Application: | S6K inhibitor |
CAS | 113963-68-1 |
MW: | 341.4 D |
From 86.00€
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