15-deoxy-Delta12,14-PGD2 is a metabolite of PGD2 (Cay-12010). It is an agonist of PGD2 receptor 2 (DP2) that binds DP2 (Ki = 50 nM for the mouse receptor expressed in HEK293 cell membranes) and induces activation of eosinophils (EC50 = 8 nM). It also stimulates the recruitment of steroid receptor coactivator-1...

Streptavidin conjugated to DyLight(R) 650 Binding Moiety: Streptavidin Reactivity: Biotin Excitation max. lambda: 562 nm Emission max. lambda: 576 nm Uses: Optimized for High throughput screening, Time-resolved fluorescence energy transfer, MicroscopyEmission: 576 nm. Excitation: 562 nm. Formulation: (Request...

15(R)-15-methyl Prostaglandin D2 (15(R)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2 (Cay-12010). The physiological actions of PGD2 include regulation of sleep, lowering of body temperature, inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 mediates its effects...

15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2 (Cay-12010). In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation. It also exhibits...

16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2. It enhances ADP-induced human platelet aggregation and increases systemic blood pressure in rats.Formal Name: 9alpha,15S-dihydroxy-16,16-dimethyl-11-oxo-prosta-5Z,13E-dien-1-oic acid. CAS Number: 64072-59-9. Synonyms: 16,16-dimethyl PGD2....