8 products were found matching "Cay12015"!

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Prostaglandin D2-1-glyceryl ester
Prostaglandin D2-1-glyceryl ester

Item number: Cay12015-1

2-Arachidonoyl glycerol (2-AG, Cay-62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Incubation of 2-AG with COX-2 and specific prostaglandin H2 (PGH2, Cay-17020) isomerases in cell cultures and isolated enzyme preparations results in...
Keywords: PGD2-1-glyceryl ester, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester
Application: Bioactive lipid assays
CAS 309260-52-4
MW: 426.6 D
From 84.00€ *
Review
JWH 175
JWH 175

Item number: Cay11201-5

JWH 175 is a synthetic cannabinoid (CB) that potently activates the central CB1 receptor (Ki = 22 nM). As a naphthylmethylindole, it is structurally related to JWH 018. The properties of this compound at the peripheral CB2 receptor or in vivo have not been characterized. This product is intended for forensic and...
Keywords: 3-(1-naphthalenylmethyl)-1-pentyl-1H-indole
Application: Analytical reference standard, Synthetic cannabinoid, Potent central CB1 receptor agonist
CAS 619294-35-8
MW: 327.5 D
From 276.00€ *
Review
3-Methylbuphedrone (hydrochloride)
3-Methylbuphedrone (hydrochloride)

Item number: Cay12001-5

Buphedrone (Cay-11486) is a substituted cathinone, analogous to methcathinone, which has been identified in products that are sold as stimulants. 3-Methylbuphedron is a methylated analog of buphedrone. Its biological and toxicological properties have not been evaluated. This product is intended for forensic and...
Keywords: 3-methyl BP, 3-Methyl-N-methylbutiophenone, 2-(methylamino)-1-(3-methylphenyl)-1-butanone, monohydrochloride
Application: Analytical reference standard, Methylated buphedrone analog
CAS 1797911-07-9
MW: 227.7 D
From 266.00€ *
Review
PF-8380
PF-8380

Item number: Cay12018-25

Autotaxin converts lysophosphatidylcholine to lysophosphatidic acid (LPA), which can mediate changes in cell proliferation, angiogenesis, and cytokine secretion. PF-8380 is a potent inhibitor of autotaxin (IC50 = 2.8 nM in an enzyme assay), the enzyme that converts lysophosphatidylcholine to lysophosphatidic acid...
Keywords: 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-(3,5-dichlorophenyl)methyl ester-1-piperazinecarboxylic acid
Application: Autotaxin Inhibitor
CAS 1144035-53-9
MW: 478.3 D
From 65.00€ *
Review
Dihydroethidium
Dihydroethidium

Item number: Cay12013-5

Dihydroethidium is a cell-permeable blue fluorescent dye that upon entering cells interacts with superoxide to form oxyethidium, which intercalates with nucleic acids and emits a red fluorescence detectable qualitatively by fluorescent microscopy or quantitatively by HPLC. It displays excitation/emission spectra of...
Keywords: Hydroethidine, PD-MY 003, 5-ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine
Application: Fluorescent dye, reactive oxygen detection
CAS 104821-25-2
MW: 315.4 D
From 60.00€ *
Review
Prostaglandin D2
Prostaglandin D2

Item number: Cay12010-5

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via...
Keywords: PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 41598-07-6
MW: 352.5 D
From 66.00€ *
Review
Prostaglandin D2 Ethanolamide
Prostaglandin D2 Ethanolamide

Item number: Cay12012-5

Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is...
Keywords: PGD2-EA, Prostamide D2, N-(2-hydroxyethyl)-11-oxo-9alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-amide
Application: Bioactive lipid assays
CAS 398138-28-8
MW: 395.5 D
From 77.00€ *
Review
8-CPT-Cyclic AMP (sodium salt)
8-CPT-Cyclic AMP (sodium salt)

Item number: Cay12011-25

8-CPT-Cyclic AMP is a lipophilic activator of the cyclic-AMP- and cyclic-GMP-dependent protein kinases, PKA and PKG (Ka = 0.05 and 0.11 µM, respectively). 8-CPT-cAMP inhibits cyclic GMP-specific phosphodiesterase (PDE VA), cyclic GMP-inhibited phosphodiesterase (PDE III), and cyclic AMP-specific phosphodiesterase...
Keywords: 8-(p-Chlorophenylthio)-cAMP, 8-CPT-cAMP, 8-[(4-chlorophenyl)thio]-cyclic 3',5'-(hydrogen phosphate)-adenosine, monosodium...
Application: PKA/PKG activator
CAS 93882-12-3
MW: 493.8 D
From 77.00€ *
Review