3 products were found matching "Cay12012-%25"!
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CAY10583
Item number: Cay10012424-25
Leukotriene B4 (LTB4) promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, superoxide anion production, chemotaxis, and chemokinesis. Two G protein-coupled receptors, BLT1 and BLT2 mediate the actions of LTB4. CAY10583 is a potent, selective full agonist for BLT2 with an EC50...
| Keywords: | 4'-[[(1-oxopentyl)phenylamino]methyl]-[1,1'-biphenyl]-2-carboxylic acid |
| Application: | BLT2 agonist |
| CAS | 862891-27-8 |
| MW: | 387.5 D |
From 82.00€
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Anti-Cbx5
Item number: ABE-11-12012-25
Chromobox homolog 5 (Cbx5), lso known as HP1 is an evolutionarily conserved non-histone chromosomal protein involved in many biological progresses, such as heterochromatin formation, transcriptional regulation, DNA recombination and damage repair, RNA interference, kinetochore protein assembly, chromatin...
| Keywords: | Anti-CBX5, Anti-HP1A, Anti-HP1 alpha, Anti-Antigen p25, Anti-Chromobox protein homolog 5, Anti-Heterochromatin protein 1... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
134.00€
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CVT-12012
Item number: Cay27156-25
CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD, IC50 = 6.1 nM in HepG2 cells). It dose-dependently reduces levels of the SCD desaturation products palmitoleic acid (Cay-10009871) and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet. CVT-12012 (20 mg/kg) also...
| Keywords: | 2-hydroxy-N-[2-[3-methyl-2-oxo-7-[[[3-(trifluoromethyl)phenyl]methyl]amino]-1(2H)-quinoxalinyl]ethyl]-acetamide |
| Application: | Stearoyl-coA desaturase (SCD) inhibitor. |
| CAS | 1018675-35-8 |
| MW: | 434.4 D |
From 43.00€
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