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PtdIns-(3,4,5)-P3-biotin (sodium salt)
Item number: Cay10009531-25
The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any...
| Keywords: | Phosphatidylinositol-3,4,5-triphosphate C-8-biotin, PIP3-biotin,... |
| Application: | Affinity probe |
| CAS | 1415684-80-8 |
| MW: | 1155.8 D |
From 212.00€
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Farnesyl Thiosalicylic Acid
Item number: Cay10010501-25
Association of Ras protein with the inner surface of the plasma membrane is required for Ras signaling activity. Farnesyl thiosalicylic acid (FTS) is an inhibitor of Ras-mediated signaling that functions by dislodging Ras from the cell membrane thereby rendering it susceptible to proteolytic degradation. FTS...
| Keywords: | FTS, Salirasib, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-benzoic acid |
| Application: | Ras signaling inhibitor |
| CAS | 162520-00-5 |
| MW: | 358.5 D |
From 54.00€
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20-hydroxy N-Arachidonoyl Taurine
Item number: Cay10009501-25
Arachidonic acid is metabolized by cytochrome P450 (CYP450) 4A omega-hydroxylase to 20-HETE, which acts as a vasoconstrictor in the kidney and brain. During mass spectrometry lipidomics analysis of rat brain, a series of fatty acyl amides of taurine was discovered, of which arachidonoyl taurine is a prominent...
| Keywords: | 20-hydroxy-2-[(1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)amino]-ethane sulfonic acid |
| Application: | Bioactive lipid assays |
| MW: | 427.6 D |
From 195.00€
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(±)10(11)-EpDPA
Item number: Cay10471-500
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid (DHA, Cay-90310) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human...
| Keywords: | (±)10,11-EDP, (±)10,11-EpDPE, (±)10,11-epoxy Docosapentaenoic Acid, (±)10,11-epoxy DPA,... |
| Application: | Soluble epoxide hydrolase substrate |
| CAS | 895127-65-8 |
| MW: | 344.5 D |
From 56.00€
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