2 products were found matching "Cay10368-%25"!

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Item number: Cay10010368-25

Raf-1 is a proto-oncogene serine/threonine protein kinase that signals from Ras to the MAPK/ERK signaling pathway. This pathway mediates basic cellular functions, including proliferation, differentiation, and survival. GW 5074 is a potent, selective, and cell-permeable inhibitor of Raf-1 (IC50 = 9 nM). It blocks...

Keywords:	3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-2H-indol-2-one
Application:	Raf-1 inhbitor
CAS	220904-83-6
MW:	520.9 D

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CAY10568

Item number: Cay10012565-25

Most local anesthetics act by abolishing voltage gated sodium channel currents indiscriminately in all populations of neurons. Selective analgesia through TRPV1-mediated entry of a cationic lidocaine derivative, QX314, was recently reported. CAY10568 is a physically smaller, less hydrophobic version of QX314...

Keywords:	Santinamide, trimethyl[(phenylcarbamoyl)methyl]-ammonium iodide
Application:	Metabolic studies
CAS	22913-17-3
MW:	320.2 D

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