- Search results for Cay10320-%25
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8 products were found matching "Cay10320-%25"!
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Item number: Cay10310-25
Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and...
Keywords: | PGA3, 9-oxo-15S-hydroxy-prosta-5Z,10,13E,17Z-tetraen-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 36614-31-0 |
MW: | 332.4 D |
From 130.00€
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Item number: Cay16300-25
Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. (±)5-iPF2alpha-VI is one of dozens of possible stereo- and regioisomeric...
Keywords: | 5-iso PGF2alpha-VI, 5-iso Prostaglandin F2alpha-VI, iPF2alpha-I, Isoprostane F2alpha-I,... |
Application: | Bioactive lipid assays |
CAS | 179094-11-2 |
MW: | 354.5 D |
From 80.00€
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Item number: Cay10010243-25
The HER2/Neu proto-oncogene is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases (RTK) which includes EGFR, HER2/Neu, HER3 and HER4. Overexpression of HER2/Neu occurs in 25-30% of human breast and ovarian cancer. AG-825 is a selective ATP-competitive inhibitor of the...
Keywords: | Tyrphostin AG-825, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide |
Application: | HER-2/neu inhibitor |
CAS | 149092-50-2 |
MW: | 397.5 D |
From 38.00€
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Item number: Cay13300-25
Bisindolylmaleimide V (BIM V) is a weak inhibitor of protein kinase C (PKC) demonstrating an IC50 value >100 µM. While effectively inactive as a PKC inhibitor, BIM V blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC50 value of 8 µM.Formal Name:...
Keywords: | BIM V, Ro 31-6045, 3,4-di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione |
Application: | S6K inhibitor |
CAS | 113963-68-1 |
MW: | 341.4 D |
From 86.00€
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Item number: Cay15300-25
IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon. It is used in the concentration range of 100 µM - 1.5 mM to induce protein expression where the gene is under the control of the lac operator and is suitable for use with X-gal or bluo-gal to detect lac gene...
Keywords: | Isopropyl beta-thiogalactoside, 1-methylethyl 1-thio-beta-D-galactopyranoside |
Application: | lac operon transcription inducer |
CAS | 367-93-1 |
MW: | 238.3 D |
From 43.00€
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Item number: Cay10010093-25
1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed...
Keywords: | 1-Oleoyl LPA, Oleoyl-sn-3-Glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid |
Application: | Bioactive lipid assays |
CAS | 65528-98-5 |
MW: | 436.5 D |
From 35.00€
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Item number: Cay10010313-25
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
Keywords: | Tyrphostin 46, Tyrphostin AG-99, 2-cyano-3-(3,4-dihydroxyphenyl)-2E-propenamide |
Application: | EGF receptor kinase inhibitor |
CAS | 122520-85-8 |
MW: | 204.2 D |
From 46.00€
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Item number: Cay10010383-25
The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 can be phosphorylated by phosphatidylinositol (PI)-3-kinase to make PtdIns-(3,4,5)-P3, which initiates...
Keywords: | 1-(1-octadecanoyl-fluorescein-2R-octanoylphosphatidyl)inositol-3,4,5-trisphosphate, heptatriethylammonium salt |
Application: | Bioactive lipid assays |
MW: | 1908.2 D |
From 115.00€
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