| Treffer 1 - 3 |  |
| ART-NR | PRODUKT | HERSTELLER | MENGE | PREIS |
| Cay10320-100 |
Enzyme kinetics  Source: recombinant N-terminal hexahistidine-tagged SET7/9 amino acids 1-366, purified from E. coli. Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated, and unlike most SET proteins, SET7/9 is exclusively a mono-methylase. SET7/9 methylates histone H3, tumor suppressor p53, and transcription factor TAF10. Recently, SET7/9 was shown to catalyze methylation of p53 in response to DNA damage thereby activating p53 for subsequent acetylation. SET7/9 is able to modulate p53 activity in a human cancer cell line, implying that it may play a significant role in human tumorigenesis. MW: 43 kD Purity: >95% |
Cayman |
100 µg |
137 €
 |
| Cay10320-25 |
Enzyme kinetics Source: recombinant N-terminal hexahistidine-tagged SET7/9 amino acids 1-366, purified from E. coli. Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated, and unlike most SET proteins, SET7/9 is exclusively a mono-methylase. SET7/9 methylates histone H3, tumor suppressor p53, and transcription factor TAF10. Recently, SET7/9 was shown to catalyze methylation of p53 in response to DNA damage thereby activating p53 for subsequent acetylation. SET7/9 is able to modulate p53 activity in a human cancer cell line, implying that it may play a significant role in human tumorigenesis. MW: 43 kD Purity: >95% |
Cayman |
25 µg |
107 €
|
| Cay10320-50 |
Enzyme kinetics Source: recombinant N-terminal hexahistidine-tagged SET7/9 amino acids 1-366, purified from E. coli. Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated, and unlike most SET proteins, SET7/9 is exclusively a mono-methylase. SET7/9 methylates histone H3, tumor suppressor p53, and transcription factor TAF10. Recently, SET7/9 was shown to catalyze methylation of p53 in response to DNA damage thereby activating p53 for subsequent acetylation. SET7/9 is able to modulate p53 activity in a human cancer cell line, implying that it may play a significant role in human tumorigenesis. MW: 43 kD Purity: >95% |
Cayman |
50 µg |
72 €
|
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|
Datenbank vom 14.06.2013, 14:39 Uhr Die Preise verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer |
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