4 products were found matching "Cay10319-%25"!

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SB 202190
SB 202190

Item number: Cay10010399-25

SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a range of other kinases, including other MAP kinases (ERKs,...
Keywords: 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol
Application: MAP kinases Inhibitor
CAS 152121-30-7
MW: 331.3 D
From 39.00€ *
Review
Lovastatin Hydroxy Acid (sodium salt)
Lovastatin Hydroxy Acid (sodium salt)

Item number: Cay10010339-25

Lovastatin hydroxy acid is a potent and competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM). It is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin (Cay-10010338).Formal Name:...
Keywords: 2-methyl-1S,2,3R,7S,8S,8aR-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthal...
Application: NF-kappaB activation inhibitor
CAS 75225-50-2
MW: 444.5 D
From 50.00€ *
Review
Dimebolin (hydrochloride)
Dimebolin (hydrochloride)

Item number: Cay10011349-25

Dimebolin is a neuroprotective agent. It binds to histamine H1 and H2 receptors (IC50s = 3.8 and 287 nM, respectively), as well as alpha1A-, alpha1B-, alpha1D-, and alpha2A-adrenergic receptors (ARs), imidazoline I2 receptors, and the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 8-313...
Keywords: Dimebon, Latrepirdine, 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indole,...
Application: Neuroprotective agent
CAS 97657-92-6
MW: 392.4 D
From 31.00€ *
Review
PAC-1
PAC-1

Item number: Cay10009317-25

Apoptosis can be induced when procaspase-3 is activated and converted to caspase-3. Procaspase-activating compound 1 (PAC-1) is a procaspase-3 activator and a potential drug treatment in cancer cell lines with elevated levels of procaspase-3. PAC-1's effectiveness was found to be directly proportional to the...
Keywords: Procaspase-activating Compound 1, 4-(phenylmethyl)-1-piperazineacetic acid,...
Application: Procaspase-3 activator
CAS 315183-21-2
MW: 392.5 D
From 145.00€ *
Review